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Table 3 Univariate and multivariate analysis of DFS

From: The impact of clinicopathologic and surgical factors on relapse and pregnancy in young patients (≤40 years old) with borderline ovarian tumors

 

Univariate

P value

Multivariate

P value

HR

95% confidence intervals

HR

95% confidence intervals

FIGO stage

Stage I

1

     

≥Stage II

2.589

1.017–6.591

0.046

1.343

0.400–4.506

0.633

Diameter

< 10 cm

1

     

≥10 cm

0.475

0.186–1.214

0.120

   

Histology

Serous

1

     

Mucinous

0.184

0.053–0.636

0.007

0.503

0.078–3.238

0.469

Othersa

0.341

0.045–2.609

0.300

1.357

0.113–16.267

0.810

Lesion lateral

Unilateralb

1

     

Bilateral

3.135

1.230–7.989

0.017

1.239

0.189–8.101

0.823

Rupture

Yes

1.229

0.353–4.284

0.746

   

No

1

     

Micropapillary

Yes

3.575

1.446–8.838

0.006

3.380

0.882–12.956

0.076

No

1

     

Microinvasion

Yes

1.461

0.334–6.381

0.614

   

No

1

     

Invasive implants

Yes

4.574

0.567–36.912

0.154

   

No

1

     

Pelvic lymph node

Positive

1.015

0.233–4.424

0.985

   

Negative

1

     

Lymphadenectomy

Yes

0.624

0.245–1.591

0.323

   

No

1

     

Surgery approach

Laparoscopy

0.886

0.115–6.830

0.908

   

Laparotomy

1

     

Adjuvant chemotherapy

Yes

3.919

0.860–17.861

0.078

   

No

1

     

Staging surgery

Yes

22.557

0.002–280,136.902

0.517

   

No

1

     

Appendectomy

Yes

0.043

0.000–318.369

0.490

   

No

1

     

Fertility sparing surgery (1)

Cystectomy

0.345

0.071–1.676

0.187

   

Bilateral cystectomy

0.527

0.063–4.399

0.554

   

Unilateral salpingo-oophorectomy

0.207

0.077–0.557

0.002

   

Unilateral salpingo-oophorectomy + contralateral cystectomy

1

     

Fertility sparing surgery (2)

 Unilateralb

Cystectomy

1.806

0.383–8.515

0.455

   

Unilateral salpingo-oophorectomy

1

     

 Bilateral

Bilateral cystectomy

0.474

0.056–3.985

0.492

   

Unilateral salpingo-oophorectomy + contralateral cystectomy

1

     

 Fertility sparing surgery (3)

Cystectomy-included

3.300

1.338–8.140

0.010

3.070

0.577–16.344

0.189

Adnexectomy

1

     
  1. aothers included endometriod, serous and mucinous; bunilateral included left and right; DFS, disease-free survival; FIGO, the International Federation of Gynecology and Obstetrics
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BMC Cancer

ISSN: 1471-2407

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