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Table 3 Univariate and multivariate analysis of DFS

From: The impact of clinicopathologic and surgical factors on relapse and pregnancy in young patients (≤40 years old) with borderline ovarian tumors

  Univariate P value Multivariate P value
HR 95% confidence intervals HR 95% confidence intervals
FIGO stage Stage I 1      
≥Stage II 2.589 1.017–6.591 0.046 1.343 0.400–4.506 0.633
Diameter < 10 cm 1      
≥10 cm 0.475 0.186–1.214 0.120    
Histology Serous 1      
Mucinous 0.184 0.053–0.636 0.007 0.503 0.078–3.238 0.469
Othersa 0.341 0.045–2.609 0.300 1.357 0.113–16.267 0.810
Lesion lateral Unilateralb 1      
Bilateral 3.135 1.230–7.989 0.017 1.239 0.189–8.101 0.823
Rupture Yes 1.229 0.353–4.284 0.746    
No 1      
Micropapillary Yes 3.575 1.446–8.838 0.006 3.380 0.882–12.956 0.076
No 1      
Microinvasion Yes 1.461 0.334–6.381 0.614    
No 1      
Invasive implants Yes 4.574 0.567–36.912 0.154    
No 1      
Pelvic lymph node Positive 1.015 0.233–4.424 0.985    
Negative 1      
Lymphadenectomy Yes 0.624 0.245–1.591 0.323    
No 1      
Surgery approach Laparoscopy 0.886 0.115–6.830 0.908    
Laparotomy 1      
Adjuvant chemotherapy Yes 3.919 0.860–17.861 0.078    
No 1      
Staging surgery Yes 22.557 0.002–280,136.902 0.517    
No 1      
Appendectomy Yes 0.043 0.000–318.369 0.490    
No 1      
Fertility sparing surgery (1) Cystectomy 0.345 0.071–1.676 0.187    
Bilateral cystectomy 0.527 0.063–4.399 0.554    
Unilateral salpingo-oophorectomy 0.207 0.077–0.557 0.002    
Unilateral salpingo-oophorectomy + contralateral cystectomy 1      
Fertility sparing surgery (2)
 Unilateralb Cystectomy 1.806 0.383–8.515 0.455    
Unilateral salpingo-oophorectomy 1      
 Bilateral Bilateral cystectomy 0.474 0.056–3.985 0.492    
Unilateral salpingo-oophorectomy + contralateral cystectomy 1      
 Fertility sparing surgery (3) Cystectomy-included 3.300 1.338–8.140 0.010 3.070 0.577–16.344 0.189
Adnexectomy 1      
  1. aothers included endometriod, serous and mucinous; bunilateral included left and right; DFS, disease-free survival; FIGO, the International Federation of Gynecology and Obstetrics