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Fig. 5 | BMC Cancer

Fig. 5

From: The hypermethylation of p16 gene exon 1 and exon 2: potential biomarkers for colorectal cancer and are associated with cancer pathological staging

Fig. 5

The p16 gene body methylation as potential biomarker of CRC. a Heat-map of the methylation of p16 exon 1 and exon 2 in CRC tissues and adjacent normal tissues (*p < 0.05). b ROC curve analysis of the p16 exon 1 methylation for distinguishing CRC and adjacent normal tissues. c ROC curve of the p16 exon 2 methylation between two groups. d ROC curve analysis of the simultaneous use of p16 exon 1 and exon 2

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