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Table 2 Associations between NDRG2 mRNA and baseline variables for the 102 CLL subjects

From: NDRG2 mRNA levels and miR-28-5p and miR-650 activity in chronic lymphocytic leukemia

  Median (95% CI) P-value
Age (years)
  ≤ 60 years 0.0015 (0–0.0303) 0.280
  > 60 years 0.0017 (0–0.0340)
Gender
 Male 0.0018 (0–0.0366) 0.194
 Female 0.0009 (0–0.0193)
Binet stage
 A 0.0036 (0.0004–0.0428) 0.001
 B/C 0.0011 (0–0.0245)
Lymphocytes (×109/L)
  < 50 0.0018 (0–0.0238) 0.618
  ≥ 50 0.0013 (0–0.0398)
LDH
  ≤ ULN 0.0025 (0–0.0303) 0.036
  > ULN 0.0008 (0–0.0375)
β2-MG
  ≤ ULN 0.0012 (0–0.0341) 0.539
  > ULN 0.0018 (0–0.0330)
CD38 (n = 100)
  < 30% 0.0020 (0–0.0358) 0.063
  ≥ 30% 0.0008 (0–0.0268)
ZAP-70 (n = 100)
  < 20% 0.0017 (0.0002–0.0389) 0.244
  ≥ 20% 0.0020 (0–0.0274)
IGHV (n = 101)
 Mutated 0.0031 (0.0002–0.0303) 0.004
 Unmutated 0.0008 (0–0.0371)
p53aberration
 No TP53 mutation or p53 deletion 0.0027 (0.0001–0.0353) < 0.001
TP53 mutation or p53 deletion 0.0003 (0–0.0009)