Table 1 Characteristics of studies included in the meta-analysis
From: MiR-20a, a novel promising biomarker to predict prognosis in human cancer: a meta-analysis
NO | Study | Year | Race | Tumor type | Clinical stage of tumor | NO(high/low) | Specimen | Detection method | Cut-off value | Outcome | Survival analyses and their source of HR | Follow-up time | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Wang et al. | 2012 | China | GC | TNM I-IV | OS: 65(34/31) | blood | qRT-PCR | median value | OS | OS: univariate(reported), multivariate(reported) | 3Â years | 8 |
2 | Chang et al. | 2013 | China | OSCC | TNM I-IV | OS: 98(71/27) | tissues | qRT-PCR | # | OS | OS: univariate(K-M Curve) | 84Â months | 8 |
3 | Cheng et al. | 2016 | China | CRC | TNM I-IV | OS, DFS: 544(407/137) | tissues | qRT-PCR | N/D | OS, DFS | OS, DFS: univariate(K-M Curve), multivariate(reported) | about 110Â months | 8 |
4 | Fan et al. | 2013 | China | HCC | tumor stage I-III | OS, RFS: 100(50/50) | tissues | qRT-PCR | N/D | OS, RFS | OS, RFS: univariate(reported), multivariate(reported) | 100Â months | 7 |
5 | Gao et al. | 2012 | China | MM | ISS: I-III, D-S: I-III | PFS: 85(43/42) | BM | qRT-PCR | N/D | PFS | PFS: univariate(K-M Curve) | 35Â months | 6 |
6 | Huang et al. | 2014 | China | GC | N/D | OS: 82(41/41) | blood | qRT-PCR | N/D | OS | OS: univariate(N/D) | about 20Â months | 6 |
7 | Marchini et al. | 2011 | Italy | EOC | Figo I substage A-C | OS, PFS: 89(N/D) | tissues | Microarray and qRT-PCR | & | OS, PFS | OS, PFS: univariate(reported), multivariate(reported) | 9Â years | 8 |
8 | Sanfiorenzo et al. | 2012 | France | NSCLC | TNM IA-B, IIA-B, IIIA | DFS: 52(N/D) | tissues and blood | qRT-PCR | median | DFS | DFS: univariate(K-M Curve), multivariate(reported) | 60Â months | 7 |
9 | Xu et al. | 2013 | China | ESCC | Clinical stage I-IV | OS: 105(54/51) | tissues | qRT-PCR | N/D | OS | OS: univariate(K-M Curve) | about 55Â months | 8 |
10 | Xu et al. | 2018 | China | NSCLC | TNM I-III | OS, DFS: 196(N/D) | blood | qRT-PCR | median | OS, DFS | OS, DFS: univariate(reported), multivariate(reported) | about 100Â months | 8 |
11 | Yang et al. | 2016 | China | GC | TNM I-IV | OS: 55(27/28) | blood | Microarray and qRT-PCR | median | OS | OS: univariate(K-M Curve) | about 35Â months | 8 |
12 | Zhang et al. | 2015 | China | CSCC | TNM I-III | OS: 152(54/98) | tissues | qRT-PCR | N/D | OS | OS: univariate(K-M Curve), multivariate(reported) | 60Â months | 6 |
13 | Zhao et al. | 2017 | China | glioblastoma | N/D | OS, DFS: 106(N/D) | blood | the nCounter Human v2 miRNA Expression Assay | N/D | OS, DFS | OS, DFS:univariate(K-M Curve), multivariate(reported) | 2Â years | 7 |
14 | Reng et al. | 2016 | China | OSCA | Figo I-IV | OS: 93(71/22) | tissues | qRT-PCR | N/D | OS | OS: univariate(K-M Curve) | about 45Â months | 5 |