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Table 1 Changes in patient and BIA variables over time

From: Bioelectrical impedance analysis for monitoring cancer patients receiving chemotherapy and home parenteral nutrition

 

T0

T1

T2

Mean Slope

(change per day)

P

Patient Variables

 Actual body weight, kg

57.4 [57.0] (33.0–100.0)

58.9 [57.0] (37.7–96.0)

59.7 [60.0] (37.5–95.0)

0.02

< 0.01

 Body Mass Index, kg/m2

21.2 [21.1] (12.7–39.1)

21.7 [21.4] (15.4–37.5)

22.0 [21.7] (15.4–37.1)

0.01

< 0.01

 Oral calorie intake, kCal

597 [600] (0–1500)

904 [1000] (0–2550)

959 [1000] (0–2550)

4.18

< 0.01

 Oral protein intake, g/day

21.1 [20.0] (0–50)

32.2 [35.0] (0–110)

34.5 [40.0] (0–90)

0.15

< 0.01

 PG-SGA category, %

A: 0%

NA

A:8%

NA

< 0.01

B: 48%

 

B:48%

  

C: 52%

 

C:44%

  

 Karnofsky PS

67.4 [70.0] (50–90)

NA

72.5 [70.0] (50–90)

NA

< 0.01

 ECOG PS

1.3 [1] (0–2)

NA

1.2 [1.0] (0–2)

NA

0.09

 Albumin, g/dL

3.4 [3.5] (1.9–4.5)

NA

3.5 [3.5] (2.2–4.6)

NA

0.19

 C-reactive protein, mg/L

16.7 [10.9] (0.4–73.2)

NA

13.5 [6.9] (0.1–140)

NA

0.23

 mGPS

1 [1] (0–2)

NA

0.6 [0] (0–2)

 

0.01

0: 37%

 

0: 62%

  

1: 26%

 

1: 14%

  

2: 37%

 

2: 25%

  

BIA Variables

 Resistance, Ohm

590.9 [606.0] (401–804)

586.6 [586.0] (401–898)

584.0 [607.0] (372–780)

−0.08

0.45

 Reactance, Ohm

52.0 [48.0] (19–120)

51.0 [49.0] (20–99)

51.2 [46.0] (22–116)

− 0.01

0.68

 Phase Angle, °

4.8 [4.8] (2.5–8.1)

5.0 [4.7] (2.5–11.4)

5.0 [4.5] (2.3–10.0)

0.00

0.32

 Total Body Water, %

59.4 [59.7] (39.3–85.8)

58.6 [58.5] (41.3–76.6)

58.0 [58.2] (41.7–76.4)

−0.02

0.04

 Extracellular Water, %,

52.1 [52.2] (25.4–70.7)

52.1 [52.6] (29.5–69.9)

52.2 [53.5] (32.3–73.2)

0.00

0.98

 Intracellular water, %

47.9 [47.8] (29.3–74.6)

48.1 [47.7] (30.1–70.5)

47.7 [46.3] (26.8–67.7)

0.00

0.89

 Fat Mass, %

23.3 [23.2] (−7.1–50.8)

24.1 [24.6] (0.5–48.4)

25.8 [24.3] (1.6–76.9)

0.03

0.04

 Fat Free Mass, %

74.6 [76.6] (49.2–86.9)

76.0 [75.4] (51.6–101.2)

75.0 [75.7] (52.5–98.4)

0.01

0.52

 Muscle Mass, %

44.0 [39.2] (25.3–75.4)

43.2 [40.0] (19.5–120.7)

42.1 [38.9] (23.5–81.3)

− 0.02

0.37

  1. All values are expressed as mean [median] (range), or percentage as indicated
  2. T0: at start of HPN; T1: 60 days after the start of HPN; T2: 90 days after the start of HPN
  3. NA Not applicable, BIA Bioelectrical impedance analysis, BMI Body mass index, ECM Extracellular mass, BCM Body cell mass, PS Performance status, ECOG Eastern cooperative oncology group, mGPS Modified Glasgow prognostic score, PG-SGA Patient-generated subjective global assessment; Category A = well-nourished; Category B = suspected malnutrition or moderate malnutrition; Category C = severely malnourished