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Table 2 Chemotherapy protocols according to patient groups

From: Human papillomavirus infection in patients with laryngeal carcinoma

  Chemotherapeutic Agent Dose Days
Group 1 (Induction CR + CRT)
 Induction Chemotherapya Cisplatin 75 mg/m2 1st
Docetaxel 75 mg/m2 1st
5-FU 750 mg/m2 1st-5th
 Concomitant Chemotherapyb Cisplatin 75 mg/m2 Once in 7 days
Group 2 (CRT)
 Concomitant Chemotherapyb Cisplatin 75 mg/m2 Once in 7 days
  1. aPatients received this protocol once in 3 weeks for 3 times. Some patients received the combination of cisplatin and docetaxel and others received the combination of cisplatin and 5-FU. Doses were modified in the range of 20–25%, based on general health status and organ functions of the patients
  2. bPatients received this protocol during radiotherapy treatment
  3. CT Chemotherapy, CRT Chemoradiotherapy