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Table 2 Chemotherapy protocols according to patient groups

From: Human papillomavirus infection in patients with laryngeal carcinoma

 

Chemotherapeutic Agent

Dose

Days

Group 1 (Induction CR + CRT)

 Induction Chemotherapya

Cisplatin

75 mg/m2

1st

Docetaxel

75 mg/m2

1st

5-FU

750 mg/m2

1st-5th

 Concomitant Chemotherapyb

Cisplatin

75 mg/m2

Once in 7 days

Group 2 (CRT)

 Concomitant Chemotherapyb

Cisplatin

75 mg/m2

Once in 7 days

  1. aPatients received this protocol once in 3 weeks for 3 times. Some patients received the combination of cisplatin and docetaxel and others received the combination of cisplatin and 5-FU. Doses were modified in the range of 20–25%, based on general health status and organ functions of the patients
  2. bPatients received this protocol during radiotherapy treatment
  3. CT Chemotherapy, CRT Chemoradiotherapy