Fig. 4

Time to treatment failure between the two groups. The Kaplan-Meier curve shows the time from treatment initiation to discontinuation for any reason between the two groups. The black line represents patients in the Pmab group and the gray line represents patients in the Cmab group. Tic marks mean censored cases. The median time to treatment failure were 223 days in the Pmab group and 200 days in the Cmab group (hazard ratio 0.78, 95% CI 0.42–1.38, P = 0.39)