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Table 3 Risk factors for developing pneumothorax in patients with sarcoma and metastatic disease to the chest

From: Secondary spontaneous pneumothorax in patients with sarcoma treated with Pazopanib, a case control study

Covariate Univariate model Multivariate model
OR 95% CI P-value OR 95% CI P-value
Age 0.981 0.963 0.999 .041  
Male 2.73 1.303 5.719 .008
Race     
White 1.000    
African American 4.047 1.589 10.307 .003
Hispanic/Other 1.827 0.780 1.278 .164
Cavitary lung nodule/mass 6.162 2.954 12.855 <.001 7.024 3.023 16.315 <.001
Pleural base lung nodule/mass 9.596 3.817 24.123 <.001 10.390 3.824 28.230 <.001
Emphysema present 8.358 0.739 94.54 .086  
Prior radiation to the chest present 2.025 0.179 22.893 .569
Patient was receiving pazopanib 2.408 0.943 6.147 .06
  1. CI = confidence interval, OR = odds ratio