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Table 4 Multivariate Cox’s Proportional Hazard Regression Model for PRS

From: Impact of the epidermal growth factor receptor mutation status on the prognosis of recurrent adenocarcinoma of the lung after curative surgery

Variable Univariate analysis Multivariate analysis
p value HR 95% CI p value
Age (> 65) 0.014 1.63 1.11–2.38 0.012
Gender (Male) 0.178    
Smoking history 0.008 1.38 0.93–2.05 0.113
Pathological T factor < 0.001 1.07 0.80–1.45 0.638
Pathological N factor 0.831    
Pathological stage 0.684    
Vessel invasion 0.722    
Lymphatic invasion 0.787    
Pleural invasion 0.659    
Systemic recurrence (vs. locoregional) 0.072    
EGFR mutation (+/−) 0.360    
Administration of EGFR - TKI < 0.001 0.60 0.40–0.89 0.012
Recurrence interval (24 < vs 24≥) 0.017 1.35 0.91–2.01 0.142
  1. PRS post-relapse survival, EGFR epidermal growth factor receptor, TKI tyrosine kinase inhibitor, HR Hazards ratio, CI Confidence interval