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Table 1 Genotype distribution of the lnc-LAMC2–1:1 rs2147578 C > G polymorphism and neuroblastoma susceptibility

From: The rs2147578 C > G polymorphism in the Inc-LAMC2–1:1 gene is associated with increased neuroblastoma risk in the Henan children

Genotype Case Control P a Crude OR
(95% CI)
P Adjusted OR
(95% CI) b
P b
Guangdong province (HWE = 0.279)
 CC 88 (32.00) 195 (36.79)   1.00   1.00  
 CG 130 (47.27) 243 (45.85)   1.19 (0.85–1.65) 0.312 1.18 (0.85–1.64) 0.332
 GG 57 (20.73) 92 (17.36)   1.37 (0.91–2.08) 0.135 1.38 (0.91–2.10) 0.127
 Additive    0.305 1.17 (0.96–1.44) 0.124 1.18 (0.96–1.44) 0.120
 Dominant 187 (68.00) 335 (63.21) 0.177 1.24 (0.91–1.68) 0.177 1.23 (0.91–1.68) 0.183
 Recessive 218 (79.27) 438 (82.64) 0.243 1.25 (0.86–1.80) 0.244 1.26 (0.87–1.82) 0.223
Henan province (HWE = 0.386)
 CC 29 (24.58) 99 (35.36)   1.00   1.00  
 CG 67 (56.78) 129 (46.07)   1.77 (1.07–2.95) 0.027 1.73 (1.03–2.89) 0.037
 GG 22 (18.64) 52 (18.57)   1.44 (0.76–2.76) 0.266 1.42 (0.74–2.74) 0.291
 Additive    0.085 1.25 (0.92–1.70) 0.158 1.23 (0.90–1.69) 0.186
 Dominant 89 (75.42) 181 (64.64) 0.036 1.68 (1.03–2.73) 0.037 1.64 (1.004–2.68) 0.048
 Recessive 96 (81.36) 228 (81.43) 0.986 1.01 (0.58–1.75) 0.986 1.00 (0.57–1.74) 1.000
Combined (HWE = 0.164)
 CC 117 (29.77) 294 (36.30)   1.00   1.00  
 CG 197 (50.13) 372 (45.93)   1.33 (1.01–1.75) 0.042 1.33 (1.01–1.75) 0.045
 GG 79 (20.10) 144 (17.78)   1.38 (0.97–1.95) 0.071 1.38 (0.97–1.95) 0.074
 Additive    0.080 1.19 (1.01–1.41) 0.043 1.19 (1.004–1.41) 0.045
 Dominant 276 (70.23) 516 (63.70) 0.025 1.34 (1.04–1.74) 0.025 1.34 (1.03–1.74) 0.028
 Recessive 314 (79.90) 666 (82.22) 0.331 1.16 (0.86–1.58) 0.331 1.16 (0.86–1.58) 0.333
  1. a χ2 test for genotype distribution in neuroblastoma cases and cancer-free controls
  2. b Adjusted for age and gender
  3. OR odds ratio, CI confidence interval
  4. The values were in bold if the 95% CI excluded 1, or P<0.05