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Fig. 7 | BMC Cancer

Fig. 7

From: Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment

Fig. 7

Schematic diagram shows that collagen I initiates ERK signaling to accelerate the aggressive progression of residual HCC cells after sublethal RFA, which could be reversed by sorafenib. More factors implicated in post-inflammation reaction after RFA promote tumor progression of residual HCC, which has been reported by the other authors [14, 15, 49, 50]

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