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Table 3 Combined effects of H19 SNPs and cooking oil fume exposure on lung cancer risk

From: Polymorphisms in the H19 gene and the risk of lung Cancer among female never smokers in Shenyang, China

SNP   Oil Controls (%) Cases (%) OR (95%CI)* P value
rs217727 CC Non-exposure 86(32.3) 59(22.0) 1(ref)  
CT + TT Non-exposure 114(42.9) 109(40.7) 1.373(0.898–2.098) 0.143
CC Exposure 27(10.2) 36(13.4) 1.921(1.055–3.501) 0.033
CT + TT Exposure 39(14.6) 64(23.9) 2.368(1.409–3.978) 0.001
rs2107425 CC Non-exposure 70(26.3) 43(16.0) 1(ref)  
CT + TT Non-exposure 130(48.9) 125(46.6) 1.550(0.985–2.439) 0.058
CC Exposure 25(9.4) 29(10.8) 1.852(0.960–3.575) 0.066
CT + TT Exposure 41(15.4) 71(26.5) 2.811(1.636–4.830) < 0.001
rs2735469 CT + TT Non-exposure 18(6.8) 10(3.7) 1(ref)  
CC Non-exposure 182(68.4) 158(59.0) 1.548(0.693–3.455) 0.286
CT + TT Exposure 9(3.4) 7(2.6) 1.388(0.395–4.876) 0.609
CC Exposure 57(21.4) 93(34.7) 2.906(1.253–6.744) 0.013
rs17658052 GG Non-exposure 188(70.7) 150(56.0) 1(ref)  
GA + AA Non-exposure 12(4.5) 18 (6.7) 1.900(0.887–4.073) 0.099
GG Exposure 62(23.3) 94(35.1) 1.897(1.289–2.792) 0.001
GA + AA Exposure 4(1.5) 6(2.2) 1.920(0.531–6.948) 0.320
  1. *: adjusted by age