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Table 3 Prevalence of comorbidities according to the Charlson Comorbidity index

From: Local ablation or radioembolization of colorectal cancer metastases: comorbidities or older age do not affect overall survival

CCIa condition n % p-value° HR (95% CI)
1 myocardial infarction, coronary artery disease 36 13,5 0.38 0.85 (0.58–1.23)
congestive heart failure 15 5,6 0.62 0.87 (0.51–1.50)
peripheral vascular disease 55 20,7 0.81 0.96 (0.71–1.31)
cerebrovascular disease 13 4,9 0.58 0.85 (0.48–1.52)
dementia 0 0   
chronic pulmonary disease 21 7,9 0.046 0.61 (0.38–0.99)
connective tissue disorder 2 0,8 0.93 0.94 (0.23–3.78)
peptic ulcer disease 2 0,8 0.006 7.40 (1.80–30.50)
mild liver disease 10 3,8 0.26 1.44 (0.76–2.72)
diabetes without complications 42 15,8 0.94 0.99 (0.70–1.40)
2 diabetes with end-organ damage 17 6,4 0.74 0.92 (0.55–1.52)
hemiplegia 1 0,4 0.70 1.48 (0.21–10.61)
moderate/severe renal disease 12 4,5 0.005 2.3 (1.29–4.13)
any tumor without metastases (incl. Leukemia, lymphoma) 34 12,8 0.89 1.03 (0.71–1.50)
3 moderate/severe liver disease 3 1,1 0.33 1.77 (0.57–5.55)
6 metastatic solid tumor (mCRC excluded) 0 0   
AIDS 0 0   
8 AIDS and any tumor 0 0   
  1. aage adjusted index CACI adds 1 point for each decade after 40 years
  2. °statistics for overall survival according to univariate Cox regression, variables with univariate p < 0.1 are processed in Table 4