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Table 3 Prevalence of comorbidities according to the Charlson Comorbidity index

From: Local ablation or radioembolization of colorectal cancer metastases: comorbidities or older age do not affect overall survival

CCIa

condition

n

%

p-value°

HR (95% CI)

1

myocardial infarction, coronary artery disease

36

13,5

0.38

0.85 (0.58–1.23)

congestive heart failure

15

5,6

0.62

0.87 (0.51–1.50)

peripheral vascular disease

55

20,7

0.81

0.96 (0.71–1.31)

cerebrovascular disease

13

4,9

0.58

0.85 (0.48–1.52)

dementia

0

0

  

chronic pulmonary disease

21

7,9

0.046

0.61 (0.38–0.99)

connective tissue disorder

2

0,8

0.93

0.94 (0.23–3.78)

peptic ulcer disease

2

0,8

0.006

7.40 (1.80–30.50)

mild liver disease

10

3,8

0.26

1.44 (0.76–2.72)

diabetes without complications

42

15,8

0.94

0.99 (0.70–1.40)

2

diabetes with end-organ damage

17

6,4

0.74

0.92 (0.55–1.52)

hemiplegia

1

0,4

0.70

1.48 (0.21–10.61)

moderate/severe renal disease

12

4,5

0.005

2.3 (1.29–4.13)

any tumor without metastases (incl. Leukemia, lymphoma)

34

12,8

0.89

1.03 (0.71–1.50)

3

moderate/severe liver disease

3

1,1

0.33

1.77 (0.57–5.55)

6

metastatic solid tumor (mCRC excluded)

0

0

  

AIDS

0

0

  

8

AIDS and any tumor

0

0

  
  1. aage adjusted index CACI adds 1 point for each decade after 40 years
  2. °statistics for overall survival according to univariate Cox regression, variables with univariate p < 0.1 are processed in Table 4