Skip to main content

Advertisement

Table 1 Main characteristics of the eligible studies

From: Tumor necrosis as a prognostic variable for the clinical outcome in patients with renal cell carcinoma: a systematic review and meta-analysis

Study Country Recruitment period No. of patients Age (years) Gender (m/f) Follow-up (months) Study design Survival analysis Surgery
Xia et al.2017 [12] China 2005–2007 293 Median (range)
55 (15–86)
90/203 Median (range)
99.1 (2.63–120.47)
Retrospective OS,PFS nephrectomy
Wu et al.2017 [13] China 2004–2012 301 Median (range)
53 (4–83)
206/95 Median (range)
51.6 (3–121)
Retrospective OS nephrectomy
Niu et al.2017 [14] China 2008–2009 384 Mean ± SD
53.9 ± 14.9
273/111 Median (range)
73 (42–74)
Retrospective OS,RFS RN and PN
Kim et al.2017 [15] Korea 2006–2012 177 Mean ± SD
62 ± 10.9
136/41 Median (range)
19.2 (0.2–63.8)
Retrospective OS,PFS nephrectomy
Gu et al.2017 [16] China 2006–2014 184 Mean ± SD
54.3 ± 13
142/42 Mean ± SD
23.3 ± 14.6
Retrospective OS, PFS nephrectomy
Gershman et al.2017 [17] USA 1980–2010 138 Mean (range)
63 (54–72)
91/47 Median (IQR)
102(67.2–130.8)
Retrospective CSS, OS RN and PN
Chen et al.2017 [18] China 2006–2015 172 Mean ± SD
56.5 ± 12.4
123/40 Mean ± SD
34.4 ± 22.9
Retrospective CSS,RFS RN
Chang1 et al.2016 [19] China 2008–2014 233 Median (IQR)
56(48–62)
170/63 Median (IQR)
68(41–71)
Retrospective RFS nephrectomy
Volpe et al.2016 [3] Italy 2000–2010 308 Median (IQR)
65(57–73)
110/80 Median (IQR)
72(39–108)
Retrospective CSS RN
Khor et al.2016 [20] USA 1985–2003 842 Median(range)
61.5(22.4–89)
527/315 Median (range)
73.2 (0.12–273.6)
Retrospective OS RN and PN
NguyenHoang et al.2016 [21] China 2008–2009 392 Mean ± SD
55.2 ± 12.1
116/276 Median (range)
73 (39–74)
Retrospective OS, RFS RN and PN
Errarte et al.2016 [22] Spain NA 59 Mean (range)
59 (25–83)
45/14 Mean (range)
65 (1–240)
Retrospective OS nephrectomy
Byun et al.2016 [23] Korea 2000–2014 1284 Mean ± SD
55.9 ± 12.9
913/371 Median (IQR)
39(19–69)
Retrospective CSS RN and PN
Huang et al.2015 [24] China 1991–2011 218 Mean ± SD
58.9 ± 12.2
169/49 Median (IQR)
43(17.8–67.5)
Retrospective RFS RN and PN
Cornejo et al.2015 [25] USA 1984–2010 154 Mean (range)
62.7 (26–86)
125/29 Mean (range)
73.9 (0.13–222)
Retrospective CSS, OS RN and PN
Teng et al.2014 [26] China 2004–2009 378 Mean ± SD
53.4 ± 12.4
272/106 Median (range)
60 (2–97)
Retrospective CSS, RFS RN and PN
Park et al.2014 [27] Korea 2006–2011 83 Mean ± SD
56.3 ± 10.5
60/23 Median (range)
18 (1–62)
Retrospective OS, PFS RN and PN
Oliveira et al.2014 [28] Brazil 1988–2006 94 Mean ± SD
59.7 ± 12.3
67/27 Median
11.7
Retrospective CSS RN and PN
Can et al.2014 [29] Turkey 1995–2012 127 Mean (range)
56 (26–80)
70/57 Mean (range)
46 (3–169)
Retrospective CSS RN and PN
Pichler et al.2013 [30] Austria 2000–2010 994 Mean ± SD
63.2 ± 11.9
599/395 Mean (range)
48.1 (0–132)
Retrospective CSS, OS RN and PN
Kruck et al.2013 [31] Germany 1993–2006 278 Mean ± SD
62.2 ± 12.5
194/84 Median (IQR)
65(20–100)
Retrospective CSS, OS RN and PN
Fukatsu et al.2013 [32] Japan 1986–2008 561 Median(range)
60(21–89)
442/119 Median (range)
55.7 (1–246)
Retrospective CSS nephrectomy
Sukov et al.2013 [33] USA 1970–2002 395 Median(range)
65(25–89)
327/68 NA Retrospective CSS RN and PN
Chang2 et al.2011 [34] China 2001–2006 328 Mean (range)
59.2 (23–89)
216/112 Mean (range)
46.5 (1.0–97.2)
Retrospective OS RN and PN
Leibovich et al.2010 [35] USA 1970–2003 3062 NA 2,0160/1002 Median (range)
97.2 (0–432)
Retrospective CSS RN and PN
Katz et al.2010 [36] USA 1989–2004 586 Median
61
530/311 Median (range)
61 (1–209)
Retrospective CSS, OS RN and PN
Roos et al.2009 [37] Germany 1990–2006 118 Mean (range)
64.5 (37.8–84.9)
76/42 Median (range)
3.2 (0.3–16.1)
Retrospective CSS, PFS nephrectomy
Coons et al.2009 [38] USA 1988–2006 128 Median(range)
64(35–87)
95/33 Median (range)
25.2 (0–124)
Retrospective CSS, OS, RFS nephrectomy
Pflanz et al.2008 [39] Germany 1992–2006 607 Mean (range)
61.6 (18–84)
387/220 Median
54
Retrospective CSS, OS RN and PN
Lee et al.2006 [40] Korea 1993–2003 485 Median(range)
55(26–81)
360/125 Median(range)
50.9(1–148.6)
Retrospective CSS RN and PN
Lam et al.2005 [41] USA 1989–2000 311 Median(range)
62(27–89)
208/103 Median (range)
45 (0.3–117)
Retrospective CSS nephrectomy
Tornberg et al.2016 [42] Finland 2006–2014 142 Median(range)
65(41–89)
95/47 Median (range)
31 (0–111)
Prospective CSS RN and cytoreductive
Schiavina et al.2015 [43] Italy 2000–2013 185 Mean ± SD
63.3 ± 11.8
149/36 Median (IQR)
32(18–62)
Prospective CSS RN and PN
Ramsey et al.2008 [44] UK 2001–2005 83 NA 50/33 Median
38
Prospective CSS, RFS nephrectomy
  1. total numbers rows:36; SD standard deviation, NA data not applicable, CSS cancer-specific survival, OS overall survival, RFS recurrence-free survival, PFS progression-free survival, RD radical nephrectomy, PN partial nephrectomy