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Table 2 baseline characteristics of the subjects included in the study

From: Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer

Variables COL11A1
COL10A1
COL11A1
COL10A1
SPARC SPARC
Healthy Controls (n = 57) Patients (n = 57) Healthy Controls (n = 90) Patients (n = 90)
Sex (%)
 Male 20 (35%) 20 (35%) 62 (69%) 62 (69%)
 Female 37 (65%) 37 (65%) 28 (31%) 28 (31%)
Age (mean,range) 66 (55–74) 65 (42–77) 66 (55–74) 66 (41–82)
Packyears (mean,range)    48 (20–112) 48 (4–158)
COPD (%)
 Present 22 (39%) 16 (28%) 48 (53%) 38 (42%)
 Absent 35 (61%) 39 (68%) 42 (47%) 50 (56%)
 NA   2 (4%)   2 (2%)
COPD severity (%)
 Severe 0 (0%) 0 (0%) 0 (0%) 2 (2%)
 Moderate 5 (9%) 2 (3%) 4 (4%) 13 (14%)
 Mild 17(30%) 14 (25%) 44 (49%) 23 (26%)
 No 35 (61%) 39 (68%) 42 (47%) 50 (56%)
 NA   2 (4%)   2 (2%)
Smoking history (%)
 Current 40 (70%) 21 (37%) 66 (73%) 64 (71%)
 Former 17 (30%) 24 (42%) 24 (27%) 26 (29%)
 Never 0 (0%) 12 (21%)   
Histology (%)
 Adenocarcinoma   47 (82%)   54 (60%)
 Squamous   10 (18%)   22 (25%)
 Others     12 (13%)
 NA     2 (2%)
Tumor stage (%)
 IA   18 (31%)   20 (22%)
 IB   3 (5%)   12 (13%)
 IIA   9 (16%)   9 (10%)
 IIB   4 (7%)   3 (3%)
 IIIA   17 (30%)   28 (31%)
 IIIB   1 (2%)   5 (6%)
 IV   5 (9%)   6 (7%)
 NA     7 (8%)
CT treatment (%)
 Yes   9 (16%)   13 (14%)
 No   48 (84%)   77 (86%)
COL11A1 (median, IQR) 0.837 (0.653–1.043) 0.923 (0.759–1.172)   
COL10A1 (median, IQR) 0.556 (0.471–0.647) 0.739 (0.640–0.882)   
SPARC (median, IQR)    0.437 (0.343–0.555) 0.676 (0.501–0.956)