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Table 1 Associations between MVDs and histopathological features

From: Angiogenesis and radiological tumor growth in patients with glioblastoma

Histopathological featuresa vWF-MVD
(Median, 95% CI, ρ)
CD105-MVD
(Median, 95% CI, ρ)
Thromboses p = 0.160 p = 0.125
 - Not present 12.0 (8.0, 21.8) 9.3 (7.2, 17.2)
 - Present 15.7 (15.5, 20.2) 13.3 (13.9, 18.4)
High cellular density p = 0.345 p = 0.082
 - Not present 14.7 (14.0, 19.3) 12.0 (12.1, 16.8)
 - Present 17.3 (14.6, 23.2) 16.3 (13.9, 21.9)
Mitotic countb p = 0.004* p = 0.001*
ρ = 0.29 ρ = 0.33
High vascular density p = 0.016* p = 0.004*
 - Not present 13.5 (12.9, 18.5) 11.3 (11.3, 15.8)
 - Present 17.5 (16.5, 24.0) 16.5 (15.2, 22.9)
  1. vWF-MVD Microvessel density count of von Willebrand factor. CD105-MVD Microvessel density count of CD105. CI Confidence interval. p: p-value. ρ Spearman correlation coefficient. a Subjectively assessed on hematoxylin-eosin sections. b Counted in hotspots for 10 high-power fields. *Statistically significant associations, p < 0.05