Fig. 1

Gompertzian growth pattern. The expected Gompertzian growth curve computed from segmented tumor volumes of two preoperative MRI scans and the interval between them in 106 patients [10]. Time is presented as a logarithmic scale. The squares represent tumor volumes at the second MRI scans: the black squares are tumor volumes with a larger increase in size than expected from their initial volume (fast-growing tumors), while the red squares are tumors with a smaller volume increase than expected from the curve (slow-growing tumors). For illustration purposes, the curve was drawn from a tumor with an arbitrary size of 0.135 mL at day 0