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Table 3 Multivariate Cox regression analysis for overall survival and relapse-free survival in gastric carcinoma patients

From: Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients

Characteristics

OS

P

RFS

P

HR (95% CI)

HR (95% CI)

TNM stage

 I

1

0.002

1

0.002

 II

1.824 (0.656–5.070)

0.250

1.838 (0.661–5.111)

0.244

 III

2.487 (0.946–6.541)

0.065

2.729 (1.040–7.159)

0.041

 IV

5.066 (1.869–13.736)

0.001

5.208 (1.922–14.113)

0.001

Venous invasion, presence (vs absence)

3.744 (2.109–6.645)

<  0.001

3.752 (2.119–6.644)

<  0.001

Ox-PTP nucleus, positive (vs negative)

9.929 (4.116–23.956)

<  0.001

10.358 (4.295–24.978)

<  0.001

  1. Abbreviations: OS overall survival, RFS relapse-free survival. Variables considered in multivariate analysis were the pretreatment serum level of CEA and CA19–9, TNM stage, tumor invasion (EGC versus AGC), venous invasion, nuclear expression of Ox-PTP, cytoplasmic expression of Ox-PTP, and ɣH2AX expression