Table 4 Enriched gene ontology (GO) biological process enriched terms associated with combined set of predicted target genes
GO biological process term | Number | Percent | p-Value | Benjamini |
|---|---|---|---|---|
positive regulation of transcription from RNA polymerase II promoter | 87 | 4.8 | 5.10E-05 | 1.60E-01 |
ubiquitin-dependent protein catabolic process | 23 | 1.3 | 5.70E-04 | 6.30E-01 |
G1/S transition of mitotic cell cycle | 13 | 0.7 | 8.50E-04 | 6.20E-01 |
positive regulation of glucose import in response to insulin stimulus | 6 | 0.3 | 4.10E-03 | 8.70E-01 |
negative regulation of canonical Wnt signaling pathway | 18 | 1 | 5.30E-03 | 9.00E-01 |
regulation of establishment of cell polarity | 6 | 0.3 | 6.40E-03 | 9.10E-01 |
regulation of cell morphogenesis | 7 | 0.4 | 7.30E-03 | 8.80E-01 |
protein autophosphorylation | 22 | 1.2 | 7.70E-03 | 8.70E-01 |
vesicle fusion | 12 | 0.7 | 7.90E-03 | 8.60E-01 |
negative regulation of apoptotic process | 35 | 1.9 | 8.90E-03 | 8.70E-01 |
regulation of small GTPase mediated signal transduction | 6 | 0.3 | 9.50E-03 | 8.70E-01 |
regulation of mRNA stability | 6 | 0.3 | 9.50E-03 | 8.70E-01 |
TOR signaling | 6 | 0.3 | 9.50E-03 | 8.70E-01 |
intrinsic apoptotic signaling pathway by p53 class mediator | 7 | 0.4 | 9.90E-03 | 8.70E-01 |
negative regulation of extrinsic apoptotic signaling pathway | 9 | 0.5 | 1.10E-02 | 8.60E-01 |
histone ubiquitination | 5 | 0.3 | 1.10E-02 | 8.40E-01 |
neuronal stem cell population maintenance | 7 | 0.4 | 1.30E-02 | 8.40E-01 |
chromatin remodeling | 12 | 0.7 | 1.50E-02 | 8.60E-01 |
response to hypoxia | 15 | 0.8 | 1.60E-02 | 8.70E-01 |
mRNA splice site selection | 5 | 0.3 | 1.80E-02 | 8.70E-01 |
miRNA mediated inhibition of translation | 5 | 0.3 | 1.80E-02 | 8.70E-01 |
regulation of gene expression | 14 | 0.8 | 2.20E-02 | 8.80E-01 |
positive regulation of cell-substrate adhesion | 8 | 0.4 | 2.80E-02 | 9.00E-01 |
histone H3-K9 trimethylation | 3 | 0.2 | 3.30E-02 | 9.20E-01 |
histone H2A ubiquitination | 3 | 0.2 | 3.30E-02 | 9.20E-01 |
polarized epithelial cell differentiation | 3 | 0.2 | 3.30E-02 | 9.20E-01 |
regulation of blood coagulation | 5 | 0.3 | 3.50E-02 | 9.20E-01 |
positive regulation of cell proliferation | 34 | 1.9 | 3.80E-02 | 9.30E-01 |
positive regulation of erythrocyte differentiation | 6 | 0.3 | 4.00E-02 | 9.30E-01 |
negative regulation of cell migration | 13 | 0.7 | 4.30E-02 | 9.40E-01 |
histone H3-K4 trimethylation | 5 | 0.3 | 4.60E-02 | 9.50E-01 |
positive regulation of apoptotic process | 21 | 1.2 | 4.60E-02 | 9.40E-01 |
stem cell population maintenance | 9 | 0.5 | 5.00E-02 | 9.50E-01 |
cell migration | 19 | 1.0 | 5.32E-02 | 9.50E-01 |