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Table 4 Enriched gene ontology (GO) biological process enriched terms associated with combined set of predicted target genes

From: Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks

GO biological process term Number Percent p-Value Benjamini
positive regulation of transcription from RNA polymerase II promoter 87 4.8 5.10E-05 1.60E-01
ubiquitin-dependent protein catabolic process 23 1.3 5.70E-04 6.30E-01
G1/S transition of mitotic cell cycle 13 0.7 8.50E-04 6.20E-01
positive regulation of glucose import in response to insulin stimulus 6 0.3 4.10E-03 8.70E-01
negative regulation of canonical Wnt signaling pathway 18 1 5.30E-03 9.00E-01
regulation of establishment of cell polarity 6 0.3 6.40E-03 9.10E-01
regulation of cell morphogenesis 7 0.4 7.30E-03 8.80E-01
protein autophosphorylation 22 1.2 7.70E-03 8.70E-01
vesicle fusion 12 0.7 7.90E-03 8.60E-01
negative regulation of apoptotic process 35 1.9 8.90E-03 8.70E-01
regulation of small GTPase mediated signal transduction 6 0.3 9.50E-03 8.70E-01
regulation of mRNA stability 6 0.3 9.50E-03 8.70E-01
TOR signaling 6 0.3 9.50E-03 8.70E-01
intrinsic apoptotic signaling pathway by p53 class mediator 7 0.4 9.90E-03 8.70E-01
negative regulation of extrinsic apoptotic signaling pathway 9 0.5 1.10E-02 8.60E-01
histone ubiquitination 5 0.3 1.10E-02 8.40E-01
neuronal stem cell population maintenance 7 0.4 1.30E-02 8.40E-01
chromatin remodeling 12 0.7 1.50E-02 8.60E-01
response to hypoxia 15 0.8 1.60E-02 8.70E-01
mRNA splice site selection 5 0.3 1.80E-02 8.70E-01
miRNA mediated inhibition of translation 5 0.3 1.80E-02 8.70E-01
regulation of gene expression 14 0.8 2.20E-02 8.80E-01
positive regulation of cell-substrate adhesion 8 0.4 2.80E-02 9.00E-01
histone H3-K9 trimethylation 3 0.2 3.30E-02 9.20E-01
histone H2A ubiquitination 3 0.2 3.30E-02 9.20E-01
polarized epithelial cell differentiation 3 0.2 3.30E-02 9.20E-01
regulation of blood coagulation 5 0.3 3.50E-02 9.20E-01
positive regulation of cell proliferation 34 1.9 3.80E-02 9.30E-01
positive regulation of erythrocyte differentiation 6 0.3 4.00E-02 9.30E-01
negative regulation of cell migration 13 0.7 4.30E-02 9.40E-01
histone H3-K4 trimethylation 5 0.3 4.60E-02 9.50E-01
positive regulation of apoptotic process 21 1.2 4.60E-02 9.40E-01
stem cell population maintenance 9 0.5 5.00E-02 9.50E-01
cell migration 19 1.0 5.32E-02 9.50E-01