Fig. 1

Venn diagram representing the number of nonsynonymous mutations in the samples with ΔCt < 1.55 and ΔCt ≥ 1.55. Each Venn diagram represents the number of nonsynonymous mutations reported in the COSMIC version 71 database with coverage ≥250, frequency ≥ 5%. In the samples with ΔCt < 1.55, nonsynonymous mutations with non-UDG pretreatment were selected (a), whereas those with UDG pretreatment were selected in the samples with ΔCt ≥ 1.55 (b)