Survival and prognostic analysis of preoperative inflammatory markers in patients undergoing surgical resection for laryngeal squamous cell carcinoma

Table 1 Correlation between preoperative NLR, PLR, MLR and baseline characteristics of patients

Variables	Parameters	n	NLR		p	PLR		p	MLR		p
Variables	Parameters	n	< 2.45	≥ 2.45	p	< 114	≥ 114	p	< 0.21	≥ 0.21	p
Age (year)	< 60	167	111	56	0.543	115	52	0.638	93	74	0.326
Age (year)	≥ 60	194	123	71	0.543	138	56	0.638	98	96	0.326
Gender	Male	353	229	124	0.814	248	105	0.934	185	168	0.364
Gender	Female	8	5	3	0.814	5	3	0.934	6	2	0.364
Tumor location	Supraglottic	280	190	90	0.080	204	76	0.025*	149	131	0.959
	Glottic	70	38	32		40	30		36	34
	Subglottic	11	6	5		9	2		6	5
T classification	T1	115	85	30	0.001*	87	28	0.006*	68	47	0.148
	T2	126	88	38		93	33		68	58
	T3	68	38	30		47	21		34	34
	T4	52	23	29		26	26		21	31
N classification	N0	320	210	110	0.416	229	91	0.221	174	146	0.081
	N1	28	15	13		16	12		14	14
	N2	13	9	4		8	5		3	10
TNM stage	I	114	85	29	0.002*	87	27	0.002*	68	46	0.094
	II	118	81	37		88	30		64	54
	III	71	40	31		49	22		36	35
	IV	58	28	30		29	29		23	35
Histology	Well	135	95	40	0.021	101	34	0.049*	73	62	0.205
	Moderate	159	105	54		113	46		89	70
	Poor	67	34	33		39	28		29	38
Laryngectomy	Partial	287	202	85	< 0.001*	216	71	< 0.001*	161	126	0.017*
Laryngectomy	Total	74	32	42	< 0.001*	37	37	< 0.001*	30	44	0.017*
Radiotherapy	No	279	180	99	0.824	198	81	0.498	143	136	0.245
Radiotherapy	Yes	82	54	28	0.824	55	27	0.498	48	34	0.245
Chemotherapy	No	335	222	113	0.039*	237	98	0.323	177	158	0.921
Chemotherapy	Yes	26	12	14	0.039*	16	10	0.323	14	12	0.921
Medication	No	314	205	99	0.016*	221	93	0.748	166	148	0.967
Medication	Yes	47	29	28	0.016*	32	15	0.748	25	22	0.967
Comorbidities	No	274	175	109	0.014*	190	84	0.586	145	129	0.994
Comorbidities	Yes	87	59	18	0.014*	63	24	0.586	46	41	0.994

Abbreviations: NLR neutrophil-lymphocyte ratio, PLR platelet-lymphocyte ratio, MLR monocyte-lymphocyte ratio
*Statistically significant p < 0.05

ISSN: 1471-2407