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Table 2 The details of all included studies

From: Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients

Reference

Year

Sample size case/controls

Ethnicity

Chemotherapy agent

Source of data

Genotyping

Cancer site

Magrangeas

2016

155/314

European

Bortezomib

RCT

SNP 6.0 Affymetrix arrays

Multiple myeloma

García-Sanz

2016

33/139

NA

Bortezomib and/or thalidomide

RCT

Axiom Exome Genotyping array (Affymetrix)

Multiple myeloma

Hertz

2016

50/566

Caucasian

Docetaxel

RCT

HumanHap610-Quad Genotyping BeadChip (Illumina)

Prostate cancer

Komatsu

2015

24/121

Asian

Paclitaxel

Cohort study

Illumina Omni-Express BeadChip

Cancer (NS)

Schneider

2015

576/781

European

Paclitaxel

RCT

HumanOmni1-Quad array (Illumina)

Breast cancer

Diouf

2015

86/235

Mixed population

Vincristine

RCT

Affymetrix GeneChip

Human Mapping 500 K array 532,552 SNPs) or the SNP 6.0 array (906,600 SNPs) (Affymetrix)

Acute lymphoblastic leukemia (ALL)

Leandro-García

2013

144

Cox regression

European

Paclitaxel

Cohort study

Infinium BeadChip Human 660WQuad assay (Illumina)

Cancer (NS)

Baldwin

2012

855

cox regression

European

Paclitaxel

RCT

HumanHap610-Quad Genotyping BeadChip (Illumina)

Breast cancer

Won

2011

39/57

Asian

Oxaliplatin

Cohort study

Affymetrix Genome-Wide

Human SNP Array 6.0

Colon cancer

  1. NA not available, RCT randomized control trial, NS not specified