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Fig. 4 | BMC Cancer

Fig. 4

From: Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes

Fig. 4

a Combination index of metformin and cisplatin. b Optical density of cisplatin in HCT-116 cells treated with cisplatin (7 μM), cisplatin nano-cubosomes (7 μM) or cisplatin (7 μM)-metformin (7 mM) nano-cubosome combination for 48 h. All data are expressed as mean ± SD of 3 separate experiments. The statistical significance of the results was analyzed using one way ANOVA followed by Tukey-Kramer multiple comparison test. *Significantly different from cisplatin (7 μM) (P < 0.05)

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