Table 2 Meta-analysis of NPM expression and clinicopathological features in solid tumors
From: Poor prognosis of nucleophosmin overexpression in solid tumors: a meta-analysis
Categories | Studies | Pooled OR | 95% CI | Heterogeneity I2(%) | P Value |
|---|---|---|---|---|---|
Age(≥60 vs. < 60) | 6 | 0.755 | 0.403–1.416 | 52.1 | 0.381 |
Gender (male vs. female) | 9 | 0.741 | 0.550–1.000 | 0.0 | 0.050 |
Tumor size (≥4 cm vs. < 4 cm) | 3 | 0.771 | 0.438–1.358 | 0.0 | 0.368 |
Tumor stage (III/IV vs. I/II) | 4 | 5.209 | 2.724–9.959 | 22.2 | < 0.001 |
Differentiation grade (poor vs. well/moderate) | 4 | 1.817 | 1.010–3.266 | 0.0 | 0.046 |