Fig. 5

Average blood vessel radius (μm) measured by PGS. a Vessel radii in the saline (RAS-unmodulated, AOM control) group remain relatively constant over the study; whereas the AOM-treated mice develop a decrease in vessel radius, most pronounced at the 16 wks time-point. b The AOM + AngII mice also show a decrease throughout the study. Decreasing vessel size may reflect sprouting new vessels. c The AOM + Losartan mice maintain a relatively constant vessel radius over the study duration. Error bars represent standard error of the mean