Table 2 Summary of LOH, expression, and enzymatic activity of Cosmc and T-synthase in human colorectal cancer samples
From: Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers
Gene | LOH | Change | mRNA level | Protein level | Enzymatic activity |
|---|---|---|---|---|---|
Cosmc | 8/15 (53%) positive | Increase | 8/15 (53%) | 18/24 (75%) | N/A |
Decrease | 2/15 (13%) | 3/24 (12%) | |||
No change | 5/15 (33%) | 3/24 (12%) | |||
T-synthase | 0/24 (0%) positive | Increase | 12/15 (80%) | 15/24 (63%) | 14/24 (58%) |
Decrease | 2/15 (13%) | 2/24 (8%) | 1/24 (4%) | ||
No change | 1/15 (7%) | 7/24 (29%) | 9/24 (38%) |