Fig. 2
From: Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins
Gn inhibits cell proliferation in colon cancer cell lines. a Gn inhibits HCT-116, HCT-116 β/W and DLD-1 cell growth (n = 3). b Colony formation assay with different doses of Gn and MP-Gr (n = 3) in HCT-116, HCT-116 β/W and DLD-1 cells. c Cell growth assay and colony formation assay in HCT-116 β/W MSI1 CRISPR knockout clones. In all figures, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05 versus DMSO control. MP-Gr or DMSO treatment is consistent with our early report [27]