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Table 2 Comparison of treatment response rate according to cumulative smoking dose

From: Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study

N = 135, N (%) Never smoker
(n = 91)
0 < PY ≤ 10
(n = 12)
10 < PY ≤ 30
(n = 22)
>  30PY
(n = 17)
p
ORR (%) 66 (72.5%) 11 (91.7%) 12 (54.5%) 6 (35.3%) 0.003
DCR (%) 83 (91.2%) 12 (100%) 18 (81.8%) 15 (88.2%) 0.39
CR, N (%) 1 (1.1%) 0 (0%) 0 (0%) 0 (0%)  
PR, N (%) 65 (71.4%) 11 (91.7%) 12 (54.5%) 6 (35.3%)  
SD, N (%) 17 (18.7%) 1 (8.3%) 6 (27.3%) 9 (52.9%)  
PD, N (%) 1 (1.2%) 0 (0%) 4 (18.2%) 2 (11.8%)  
unevaluable 7 (7.7%) 0 (0%) 0 (0%) 0 (0%)  
  1. Abbreviation: PY pack-years, ORR objective response rate, DCR disease control rate, CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR(CR + PR), DCR(CR + PR + SD)