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Table 2 Comparison of treatment response rate according to cumulative smoking dose

From: Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study

N = 135, N (%)

Never smoker

(n = 91)

0 < PY ≤ 10

(n = 12)

10 < PY ≤ 30

(n = 22)

>  30PY

(n = 17)

p

ORR (%)

66 (72.5%)

11 (91.7%)

12 (54.5%)

6 (35.3%)

0.003

DCR (%)

83 (91.2%)

12 (100%)

18 (81.8%)

15 (88.2%)

0.39

CR, N (%)

1 (1.1%)

0 (0%)

0 (0%)

0 (0%)

 

PR, N (%)

65 (71.4%)

11 (91.7%)

12 (54.5%)

6 (35.3%)

 

SD, N (%)

17 (18.7%)

1 (8.3%)

6 (27.3%)

9 (52.9%)

 

PD, N (%)

1 (1.2%)

0 (0%)

4 (18.2%)

2 (11.8%)

 

unevaluable

7 (7.7%)

0 (0%)

0 (0%)

0 (0%)

 
  1. Abbreviation: PY pack-years, ORR objective response rate, DCR disease control rate, CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR(CR + PR), DCR(CR + PR + SD)
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BMC Cancer

ISSN: 1471-2407

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