Fig. 7
From: Loss of PDPK1 abrogates resistance to gemcitabine in label-retaining pancreatic cancer cells
PDPK1 knockdown decreases resistance to gemcitabine in the LRCC population. a Proliferation of MiaPaCa2, Panc-1, and Nor-P1 cells exposed to gemcitabine at GI50 concentration for two doubling times and normalized to vehicle-treated when treated with scramble siRNA (left) and PDPK1 siRNA (right) (*p < 0.05, **p < 0.01, ***p < 0.001; paired t-test), and b) induced apoptosis measured by caspase3/7 levels