Table 3 Cytoplasmic and nuclear TRAIL-R1 expression in malignant and non-malignant ducts
From: Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC
cytoplasm | nuclei | |||||||
|---|---|---|---|---|---|---|---|---|
a) | n | % | n | % | ||||
Positive tumor cells | ||||||||
0% | 7 | 6.6 | 70 | 66.0 | ||||
< 10% | 5 | 4.8 | 9 | 8.5 | ||||
11–50% | 11 | 10.4 | 16 | 15.1 | ||||
51–80% | 22 | 20.8 | 10 | 9.4 | ||||
> 80% | 61 | 57.5 | 1 | 0.9 | ||||
Staining intensity | ||||||||
Negative | 7 | 6.6 | 70 | 66.0 | ||||
Weak positive | 55 | 51.9 | 28 | 26.4 | ||||
Moderate positive | 24 | 22.6 | 8 | 7.5 | ||||
Strong positive > 80% | 20 | 18.9 | 0 | 0.0 | ||||
Sum score | ||||||||
0 | 7 | 6.6 | 70 | 66.0 | ||||
2 | 4 | 3.8 | 9 | 8.5 | ||||
3–4 | 25 | 23.6 | 21 | 19.8 | ||||
5–6 | 57 | 53.8 | 6 | 5.7 | ||||
7 | 13 | 13.0 | 0 | 0.0 | ||||
b) | tumor | non-malignant | tumor | non-malignant | ||||
n | % | n | % | n | % | n | % | |
Staining intensity | ||||||||
Negative | 7 | 6.6 | 3 | 10.7 | 70 | 66.0 | 26 | 92.9 |
Weak positive | 55 | 51.9 | 14 | 50.0 | 28 | 26.4 | 2 | 7.1 |
Moderate positive | 24 | 22.6 | 6 | 21.5 | 8 | 7.5 | 0 | 0.0 |
Strong positive | 20 | 18.9 | 5 | 17.9 | 0 | 0.0 | 0 | 0.0 |
Staining pattern: tumor vs. non-malignant | no difference ns, p = 0.698 | p = 0.006 | ||||||