Skip to main content

Table 1 The intra-group comparisons of texture parameters in the control, paclitaxel and combination therapy groups

From: A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis

SSF

Pre-treatment

Mid-treatment

Post-treatment

P value

mean

SD

entropy

MPP

mean

SD

entropy

MPP

mean

SD

entropy

MPP

mean

SD

entropy

MPP

A. Texture parameters in the control group

 

0

1725.70 ± 139.32

289.54 ± 24.82

6.12 ± 0.18

1725.70 ± 139.32

1599.25 ± 90.58

311.06 ± 29.68

6.55 ± 0.07

1599.25 ± 90.58

1658.22 ± 148.93

341.60 ± 39.17

6.74 ± 0.05

1658.22 ± 148.93

0.330

0.105

0.002*

0.330

2

1195.15 ± 808.31

1056.11 ± 345.60

6.48 ± 0.32

1579.19 ± 425.70

817.32 ± 638.70

1138.52 ± 313.80

7.22 ± 0.11

1373.25 ± 305.27

1351.10 ± 94.28

1028.40 ± 141.74

7.53 ± 0.10

1537.98 ± 79.00

0.651

0.733

0.002*

0.677

3

2075.70 ± 815.16

1379.17 ± 426.13

6.53 ± 0.30

2266.05 ± 692.00

1331.32 ± 712.57

1111.32 ± 122.70

7.21 ± 0.08

1649.98 ± 518.25

1955.66 ± 266.91

962.22 ± 103.47

7.49 ± 0.13

1997.08 ± 237.50

0.196

0.031*

0.002*

0.196

4

2589.17 ± 737.94

1449.94 ± 405.76

6.52 ± 0.32

2758.20 ± 605.26

1816.10 ± 679.22

1243.09 ± 352.48

7.22 ± 0.07

2121.33 ± 504.72

2524.37 ± 430.15

987.92 ± 144.55

7.51 ± 0.12

2533.12 ± 419.03

0.228

0.179

0.002*

0.230

5

2982.66 ± 619.22

1321.09 ± 420.85

6.51 ± 0.31

3037.58 ± 567.00

2304.45 ± 604.56

1317.59 ± 488.49

7.23 ± 0.12

2556.24 ± 476.15

3032.57 ± 522.03

1072.23 ± 139.86

7.51 ± 0.15

3032.57 ± 522.03

0.141

0.403

0.003*

0.185

6

3390.92 ± 537.48

1161.66 ± 396.02

6.50 ± 0.31

3390.92 ± 537.48

2816.54 ± 544.16

1289.99 ± 452.01

7.21 ± 0.13

2883.07 ± 518.08

3444.29 ± 569.76

1108.20 ± 113.03

7.56 ± 0.11

3444.29 ± 569.76

0.134

0.733

0.002*

0.164

B. Texture parameters in the paclitaxel group

0

1792.59 ± 269.74

294.36 ± 31.16

6.20 ± 0.07

1792.59 ± 269.74

1720.35 ± 154.36

319.42 ± 95.00

6.57 ± 0.17

1720.35 ± 154.36

1723.30 ± 132.64

343.89 ± 33.77

6.71 ± 0.08

1723.30 ± 132.64

0.970

0.185

0.005*

0.970

2

1506.90 ± 971.82

1098.25 ± 196.70

6.65 ± 0.16

1775.18 ± 729.63

1425.57 ± 422.54

1195.67 ± 413.08

7.34 ± 0.26

1799.71 ± 207.05

1732.09 ± 387.71

1072.68 ± 138.56

7.55 ± 0.26

1867.67 ± 304.82

0.595

0.932

0.008*

0.970

3

2180.45 ± 944.57

1243.56 ± 484.91

6.65 ± 0.21

2413.68 ± 750.85

2140.12 ± 281.63

1116.57 ± 234.65

7.32 ± 0.25

2226.54 ± 155.82

2542.73 ± 582.90

1054.99 ± 156.52

7.52 ± 0.22

2557.25 ± 575.12

0.619

0.914

0.006*

0.914

4

2703.43 ± 918.57

1423.35 ± 694.75

6.66 ± 0.24

2862.68 ± 929.52

2668.49 ± 298.86

1093.71 ± 243.84

7.31 ± 0.24

2681.39 ± 299.52

3136.81 ± 686.17

1184.75 ± 233.59

7.56 ± 0.23

3145.29 ± 677.08

0.595

0.651

0.005*

0.566

5

3076.44 ± 1148.06

1401.55 ± 733.68

6.65 ± 0.21

3157.93 ± 794.39

3063.26 ± 529.59

1103.85 ± 390.31

7.28 ± 0.30

3075.22 ± 541.38

3509.64 ± 706.55

1268.90 ± 275.16

7.59 ± 0.26

3513.13 ± 703.86

0.566

0.691

0.005*

0.482

6

3383.79 ± 901.65

1256.03 ± 624.43

6.64 ± 0.21

3405.85 ± 715.29

3396.54 ± 717.25

1057.56 ± 423.29

7.27 ± 0.31

3396.54 ± 717.25

3718.2 ± 673.68

1204.06 ± 274.35

7.58 ± 0.29

3718.2 ± 673.68

0.691

0.878

0.005*

0.691

C. Texture parameters in the combination therapy group

0

1806.38 ± 205.10

312.10 ± 66.52

6.10 ± 0.20

1806.38 ± 205.10

1678.27 ± 95.64

312.68 ± 59.26

6.43 ± 0.15

1678.27 ± 95.64

1884.06 ± 121.01

375.78 ± 41.57

6.68 ± 0.11

1884.06 ± 121.01

0.055

0.143

0.001*

0.055

2

1433.12 ± 720.31

1311.13 ± 379.57

6.43 ± 0.24

1894.66 ± 453.57

1854.46 ± 321.90

955.21 ± 131.04

7.07 ± 0.14

1927.35 ± 338.02

1910.08 ± 315.32

1212.64 ± 200.58

7.45 ± 0.15

2081.77 ± 351.62

0.368

0.064

0.001*

0.630

3

2448.26 ± 419.37

1599.97 ± 672.77

6.46 ± 0.26

2821.10 ± 506.02

2488.27 ± 377.97

1012.94 ± 139.51

7.09 ± 0.12

2504.52 ± 373.95

2791.28 ± 384.04

1334.57 ± 134.55

7.48 ± 0.16

2893.49 ± 361.47

0.318

0.030*

0.001*

0.164

4

3011.07 ± 359.31

1471.26 ± 652.16

6.42 ± 0.29

3154.51 ± 477.70

2785.42 ± 425.84

892.06 ± 122.07

7.04 ± 0.13

2788.44 ± 422.44

3433.14 ± 429.29

1308.58 ± 164.02

7.46 ± 0.16

3446.67 ± 417.53

0.029*

0.019*

0.001*

0.050

5

3355.47 ± 524.72

1295.85 ± 608.95

6.40 ± 0.32

3395.32 ± 561.31

2965.52 ± 528.24

811.48 ± 135.21

6.97 ± 0.16

2965.52 ± 528.24

3867.23 ± 421.55

1251.75 ± 188.81

7.43 ± 0.17

3867.23 ± 421.55

0.025*

0.023*

0.001*

0.034*

6

3678.70 ± 683.91

1115.19 ± 538.41

6.40 ± 0.29

3680.00 ± 685.25

3136.03 ± 593.59

763.13 ± 151.67

6.99 ± 0.19

3136.03 ± 593.58

4154.52 ± 361.67

1163.57 ± 163.15

7.42 ± 0.17

4154.52 ± 361.67

0.045*

0.024*

0.001*

0.045*

  1. *“means P < 0.05