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Table 1 The intra-group comparisons of texture parameters in the control, paclitaxel and combination therapy groups

From: A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis

SSF Pre-treatment Mid-treatment Post-treatment P value
mean SD entropy MPP mean SD entropy MPP mean SD entropy MPP mean SD entropy MPP
A. Texture parameters in the control group  
0 1725.70 ± 139.32 289.54 ± 24.82 6.12 ± 0.18 1725.70 ± 139.32 1599.25 ± 90.58 311.06 ± 29.68 6.55 ± 0.07 1599.25 ± 90.58 1658.22 ± 148.93 341.60 ± 39.17 6.74 ± 0.05 1658.22 ± 148.93 0.330 0.105 0.002* 0.330
2 1195.15 ± 808.31 1056.11 ± 345.60 6.48 ± 0.32 1579.19 ± 425.70 817.32 ± 638.70 1138.52 ± 313.80 7.22 ± 0.11 1373.25 ± 305.27 1351.10 ± 94.28 1028.40 ± 141.74 7.53 ± 0.10 1537.98 ± 79.00 0.651 0.733 0.002* 0.677
3 2075.70 ± 815.16 1379.17 ± 426.13 6.53 ± 0.30 2266.05 ± 692.00 1331.32 ± 712.57 1111.32 ± 122.70 7.21 ± 0.08 1649.98 ± 518.25 1955.66 ± 266.91 962.22 ± 103.47 7.49 ± 0.13 1997.08 ± 237.50 0.196 0.031* 0.002* 0.196
4 2589.17 ± 737.94 1449.94 ± 405.76 6.52 ± 0.32 2758.20 ± 605.26 1816.10 ± 679.22 1243.09 ± 352.48 7.22 ± 0.07 2121.33 ± 504.72 2524.37 ± 430.15 987.92 ± 144.55 7.51 ± 0.12 2533.12 ± 419.03 0.228 0.179 0.002* 0.230
5 2982.66 ± 619.22 1321.09 ± 420.85 6.51 ± 0.31 3037.58 ± 567.00 2304.45 ± 604.56 1317.59 ± 488.49 7.23 ± 0.12 2556.24 ± 476.15 3032.57 ± 522.03 1072.23 ± 139.86 7.51 ± 0.15 3032.57 ± 522.03 0.141 0.403 0.003* 0.185
6 3390.92 ± 537.48 1161.66 ± 396.02 6.50 ± 0.31 3390.92 ± 537.48 2816.54 ± 544.16 1289.99 ± 452.01 7.21 ± 0.13 2883.07 ± 518.08 3444.29 ± 569.76 1108.20 ± 113.03 7.56 ± 0.11 3444.29 ± 569.76 0.134 0.733 0.002* 0.164
B. Texture parameters in the paclitaxel group
0 1792.59 ± 269.74 294.36 ± 31.16 6.20 ± 0.07 1792.59 ± 269.74 1720.35 ± 154.36 319.42 ± 95.00 6.57 ± 0.17 1720.35 ± 154.36 1723.30 ± 132.64 343.89 ± 33.77 6.71 ± 0.08 1723.30 ± 132.64 0.970 0.185 0.005* 0.970
2 1506.90 ± 971.82 1098.25 ± 196.70 6.65 ± 0.16 1775.18 ± 729.63 1425.57 ± 422.54 1195.67 ± 413.08 7.34 ± 0.26 1799.71 ± 207.05 1732.09 ± 387.71 1072.68 ± 138.56 7.55 ± 0.26 1867.67 ± 304.82 0.595 0.932 0.008* 0.970
3 2180.45 ± 944.57 1243.56 ± 484.91 6.65 ± 0.21 2413.68 ± 750.85 2140.12 ± 281.63 1116.57 ± 234.65 7.32 ± 0.25 2226.54 ± 155.82 2542.73 ± 582.90 1054.99 ± 156.52 7.52 ± 0.22 2557.25 ± 575.12 0.619 0.914 0.006* 0.914
4 2703.43 ± 918.57 1423.35 ± 694.75 6.66 ± 0.24 2862.68 ± 929.52 2668.49 ± 298.86 1093.71 ± 243.84 7.31 ± 0.24 2681.39 ± 299.52 3136.81 ± 686.17 1184.75 ± 233.59 7.56 ± 0.23 3145.29 ± 677.08 0.595 0.651 0.005* 0.566
5 3076.44 ± 1148.06 1401.55 ± 733.68 6.65 ± 0.21 3157.93 ± 794.39 3063.26 ± 529.59 1103.85 ± 390.31 7.28 ± 0.30 3075.22 ± 541.38 3509.64 ± 706.55 1268.90 ± 275.16 7.59 ± 0.26 3513.13 ± 703.86 0.566 0.691 0.005* 0.482
6 3383.79 ± 901.65 1256.03 ± 624.43 6.64 ± 0.21 3405.85 ± 715.29 3396.54 ± 717.25 1057.56 ± 423.29 7.27 ± 0.31 3396.54 ± 717.25 3718.2 ± 673.68 1204.06 ± 274.35 7.58 ± 0.29 3718.2 ± 673.68 0.691 0.878 0.005* 0.691
C. Texture parameters in the combination therapy group
0 1806.38 ± 205.10 312.10 ± 66.52 6.10 ± 0.20 1806.38 ± 205.10 1678.27 ± 95.64 312.68 ± 59.26 6.43 ± 0.15 1678.27 ± 95.64 1884.06 ± 121.01 375.78 ± 41.57 6.68 ± 0.11 1884.06 ± 121.01 0.055 0.143 0.001* 0.055
2 1433.12 ± 720.31 1311.13 ± 379.57 6.43 ± 0.24 1894.66 ± 453.57 1854.46 ± 321.90 955.21 ± 131.04 7.07 ± 0.14 1927.35 ± 338.02 1910.08 ± 315.32 1212.64 ± 200.58 7.45 ± 0.15 2081.77 ± 351.62 0.368 0.064 0.001* 0.630
3 2448.26 ± 419.37 1599.97 ± 672.77 6.46 ± 0.26 2821.10 ± 506.02 2488.27 ± 377.97 1012.94 ± 139.51 7.09 ± 0.12 2504.52 ± 373.95 2791.28 ± 384.04 1334.57 ± 134.55 7.48 ± 0.16 2893.49 ± 361.47 0.318 0.030* 0.001* 0.164
4 3011.07 ± 359.31 1471.26 ± 652.16 6.42 ± 0.29 3154.51 ± 477.70 2785.42 ± 425.84 892.06 ± 122.07 7.04 ± 0.13 2788.44 ± 422.44 3433.14 ± 429.29 1308.58 ± 164.02 7.46 ± 0.16 3446.67 ± 417.53 0.029* 0.019* 0.001* 0.050
5 3355.47 ± 524.72 1295.85 ± 608.95 6.40 ± 0.32 3395.32 ± 561.31 2965.52 ± 528.24 811.48 ± 135.21 6.97 ± 0.16 2965.52 ± 528.24 3867.23 ± 421.55 1251.75 ± 188.81 7.43 ± 0.17 3867.23 ± 421.55 0.025* 0.023* 0.001* 0.034*
6 3678.70 ± 683.91 1115.19 ± 538.41 6.40 ± 0.29 3680.00 ± 685.25 3136.03 ± 593.59 763.13 ± 151.67 6.99 ± 0.19 3136.03 ± 593.58 4154.52 ± 361.67 1163.57 ± 163.15 7.42 ± 0.17 4154.52 ± 361.67 0.045* 0.024* 0.001* 0.045*
  1. *“means P < 0.05