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Table 1 Clinicopathologic characteristics of the patients in the five HGG data sets

From: Clinical significance of FBXO17 gene expression in high-grade glioma

  TCGA Rembrandt 1b Rembrandt 2c GSE4271 GSE4412
No. of patientsa 424 183 247 77 85
Age, median (range) 58.9 (10.9–89.3) 50 (20–80) 50 (15–80) 45 (22–82) 42 (18–82)
Sex
 Female 159 (37.5) 47 (36.4) 67 (38.5) 25 (32.5) 53 (62.4)
 Male 265 (62.5) 82 (63.6) 107 (61.5) 52 (67.5) 32(37.6)
 NA 0 54 73 0 0
Grade
 III 0 (0) 0 (0) 64 (25.9) 21 (27.3) 26 (30.6)
 IV (GBM) 424 (100) 183 (100) 183 (74.1) 56 (72.7) 59 (69.4)
Vital Status
 Alive 75 (17.7) 10 (5.5) 21 (8.5) 15 (19.5) 26 (30.6)
 Dead 349 (82.3) 173 (94.5) 226 (91.5) 62 (80.5) 59 (69.4)
Median OS in months 14.2 15 16 23.8 13.9
  1. Values are reported as No. (%) unless otherwise indicated. Missing values are excluded from the percentage calculation. NA not applicable
  2. aSamples with both OS (vital status) and gene expression data
  3. bGBM sample only from Rembrandt database
  4. cGBM and Grade III astrocytoma/oligodendroglioma from Rembrandt database