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Fig. 10 | BMC Cancer

Fig. 10

From: Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer

Fig. 10

Microarray analysis of changes in the gene expression and signaling pathways affected by BAG3 knockout in HCT-116 cells. a Heat map representation of 1224 genes with significant differential expression in HCT-116 cells with or without BAG3 knockout. b Functional pathway enrichment analysis using IPA. c Microarray data were further confirmed by qRT-PCR analysis of selected genes. d Gene interaction network in HCT-116 cells after BAG3 knockout. Green represents downregulated genes, while red represents upregulated genes. The solid lines represent direct interactions, while the dotted lines represent indirect interactions

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BMC Cancer

ISSN: 1471-2407

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