Table 1 Clinicopathological features of female cats with mammary carcinoma enrolled in this study (n = 115)
Clinicopathological feature | No. of animals (%) | Clinicopathological feature | No. of animals (%) |
|---|---|---|---|
Age (Mean ± SD) | 11.40 ± 2.82 years | HP classification | |
<10 years | 32 (27.8) | Papillary-cystic carcinoma | 7 (6.1) |
≥10 years | 79 (68.7) | Cribriform carcinoma | 10 (8.7) |
Unknown | 4 (3.5) | Mucinous carcinoma | 11 (9.5) |
Solid carcinoma | 20 (17.4) | ||
Tubular carcinoma | 30 (26.1) | ||
Tubulopapillary carcinoma | 37 (32.2) | ||
Breed | Malignancy grade | ||
Not determined | 95 (82.6) | I | 3 (2.6) |
Siamese | 10 (8.7) | II | 21 (18.3) |
Persian | 7 (6.1) | III | 91 (79.1) |
Norwegian Forest Cat | 3 (2.6) | ||
Spayed | Necrosis | ||
No | 59 (51.3) | No | 30 (26.1) |
Yes | 52 (45.2) | Yes | 85 (73.9) |
Unknown | 4 (3.5) | ||
Contraceptives | Lymphatic invasion | ||
No | 35 (30.4) | No | 91 (79.1) |
Yes | 53 (46.1) | Yes | 24 (20.9) |
Unknown | 27 (23.5) | ||
Treatment | Lymphocytic infiltration | ||
Mastectomy | 97 (84.3) | No | 33 (28.7) |
Mastectomy + Chemo | 8 (7.0) | Yes | 80 (69.6) |
None | 10 (8.7) | Unknown | 2 (1.7) |
Multiple mammary tumors | Tumor ulceration | ||
No | 42 (36.5) | No | 96 (83.5) |
Yes | 73 (63.5) | Yes | 19 (16.5) |
Disease stage (TNM) | Ki-67 index | ||
I | 25 (21.7) | Low (<14%) | 31 (26.9) |
II | 20 (17.4) | High (≥14%) | 83 (72.2) |
III | 52 (45.2) | Unknown | 1 (0.9) |
IV | 13 (11.3) | ||
Not determined | 5 (4.4) | ||
Lymph node status | PR status | ||
Negative | 61 (53.0) | Negative | 66 (57.4) |
Positive | 44 (38.3) | Positive | 49 (42.6) |
Unknown | 10 (8.7) | ||
Localization | ER status | ||
M1 | 17 (14.8) | Negative | 86 (74.8) |
M2 | 22 (19.1) | Positive | 29 (25.2) |
M3 | 43 (37.4) | ||
M4 | 26 (22.6) | ||
Unknown | 7 (6.1) | ||
Recurrence | HER2 status | ||
No | 39 (33.9) | Negative | 83 (72.2) |
Yes | 64 (55.7) | Positive | 32 (27.8) |
Unknown | 12 (10.4) | ||
Survival | Serum CXCL12 levels | ||
No | 53 (46.1) | Negative (<2 ng/ml) | 17 (14.8) |
Yes | 58 (50.4) | Positive (≥2 ng/ml) | 25 (21.7) |
Unknown | 4 (3.5) | Not determined | 73 (63.5) |
Tumor size | |||
≤1 cm | 21 (18.3) | ||
>1 cm | 94 (81.7) | ||