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Table 1 Patient demographics and disease characteristics

From: Phase II trial of eribulin mesylate as a first- or second-line treatment for locally advanced or metastatic breast cancer: a multicenter, single-arm trial

 

No. of patients

%

Age, years

 Median

66

 Range

39–82

ECOG performance status

 0

25

78.1

 1

5

15.6

 2

2

6.3

(Neo-)adjuvant chemotherapy

22

68.7

 Anthracycline

7

21.9

 Taxane

2

6.3

 Anthracycline + taxan

11

34.4

 Oral 5FU

1

3.1

 CMF

1

3.1

Adjuvant endocrine therapy

14

43.7

Prior endocrine therapy for advanced disease

15

46.9

No. of prior chemotherapy regimens for advanced disease

 0

22

68.8

 1

10

31.3

 Taxan

5

15.6

 Oral 5FU (capecitabine or S-1)

5

15.6

ER-postive

19

59.4

PgR-positive

18

56.3

HER2-positive

1

3.1

Triple negatve

11

33.3

Metastatic site

 Liver

14

43.8

 Lung

14

43.8

 Brain

0

0

 Bone

13

40.6

 Skin

8

25

 Other

14

43.8

No of organs involved

 1

9

28.1

 2

13

40.6

 3

5

15.6

 4

5

15.6

Site of disease

 Viceral

23

71.9

  1. Abbreviations: ECOG Eastrern cooperative oncology group, ER estrogen receptor, PgR progesterone receptor, HER2 human epidermal growth factor receptor 2