Table 3 FAO signature expression is prognostic in independent breast cancer datasets
From: Fatty acid oxidation is associated with proliferation and prognosis in breast and other cancers
Dataset | Study | n | Log rank p (survival metric) | Hazard ratio (Low vs. High) | Hazard ratio (95% confidence interval) | FDR adjusted p |
|---|---|---|---|---|---|---|
GSE42568 | Clarke et al. | 104 | 0.00562 (RFS) | 2.24 | 1.25–4.03 | 0.007 |
|  |  | 104 | 0.0000958 (OS) | 4.05 | 1.84–8.66 | 0.000311 |
GSE20685 | Kao et al. | 327 | 0.0118 (DMFS) | 1.98 | 1.26–3.11 | 0.003 |
|  |  | 327 | 0.00243 (OS) | 1.75 | 1.12–2.27 | 0.013 |
GSE46563 | Jonsdottir et al. | 94 | 0.000543 (DMFS) | 5.46 | 1.86–16.1 | 0.002 |
GSE25066 | Hatzis et al. | 508 | 5.98E-06 | 2.43 | 1.64–3.62 | 1.17E-05 |
TCGA BRCA | TCGA breast cancer | 776 | 0.00387 (RFS) | 2.08 | 1.25–3.47 | 0.0047 |
|  |  | 1096 | 0.097 (OS) | 1.31 | 0.95–1.81 | 0.097 |
GSE22219 | Buffa et al. | 216 | 0.00753 (DRFS) | 1.82 | 1.17–2.85 | 0.0085 |
BRCA2116 | Nagalla et al. | 672 | 6.51E-05 (DRFS) | 2.02 | 1.42–2.88 | 9.10E-05 |
GSE21653 | Sabatier et al. | 266 | 0.03 (DFS) | 1.64 | 1.06–2.55 | 0.03 |