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Table 2 Response to anti PD-1 according to BRAF status

From: Ineffective anti PD-1 therapy after BRAF inhibitor failure in advanced melanoma

  Wild-type BRAF Mutated BRAF p
n = 33 n = 41
Objective Response Rate, n (%) 15 (45.5) 5 (12.2) 0.003
Disease Control Rate, n (%) 19 (57.6) 10 (24.4) 0.008
Progressive Disease, n (%) 14 (42.4) 31 (42.4)  
Median Progression-Free Survival, months [95%CI] 5 [0.2–9.8] 2 [1.6–2.4] < 0.001
Median Overall Survival, months [95%CI] 20 [5.4–34.6] 7 [4.0–10.0] < 0.001
  1. CI confidence interval