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Fig. 1 | BMC Cancer

Fig. 1

From: Gene promoter and exon DNA methylation changes in colon cancer development – mRNA expression and tumor mutation alterations

Fig. 1

Global DNA methylation alterations of the normal-adenoma-colorectal cancer sequence. a DNA methylation of LINE-1 (long interspersed nuclear element-1) in CRC, adenoma and normal tissue samples. N = normal, Ad = adenoma, CRC = colorectal cancer; b Category distribution of global DNA methylation in CRC, adenoma and NAT samples analyzed by methyl capture sequencing. DNA methylation percentage categories are shown on the X axis, while the numbers of 100 base pair analysis windows are represented on the Y axis. NAT = normal adjacent tissue, AD = adenoma, CRC = colorectal cancer.

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