Skip to main content

Table 1 Quantitative parameters between the responder and non-responder groups

From: MRI in predicting the response of gastrointestinal stromal tumor to targeted therapy: a patient-based multi-parameter study

Time point Responder Non-responder F P
ADC (mm2/s)    19.378 < 0.001
 Baseline 1.18 ± 0.27 1.17 ± 0.31 0.001 0.972
 Week 2 1.60 ± 0.40 1.19 ± 0.38 13.620 < 0.001
 Week 12 1.99 ± 0.56 1.20 ± 0.31 33.293 < 0.001
LD (mm)    0.15 0.700
 Baseline 70.58 ± 33.40 59.16 ± 40.55 0.914 0.343
 Week 2 63.51 ± 29.79 58.98 ± 38.33 0.125 0.725
 Week 12 48.07 ± 27.86 71.57 ± 46.37 6.044 0.017
T2WI-CNR    0.359 0.551
 Baseline 39.28 ± 22.62 30.32 ± 18.19 1.930 0.170
 Week 2 41.56 ± 24.22 37.43 ± 24.21 0.920 0.341
 Week 12 36.29 ± 23.41 40.82 ± 28.27 0.429 0.515
%ΔADC = (ADCpost - ADCpre) / ADCpre   t/Z P
Week 2 0.30 (−0.03, 1.38) 0.01(−0.29, 0.30) − 4.819 < 0.001
Week 12 0.67 (−0.07, 3.13) 0.06 (− 0.26, 0.52) −4.890 < 0.001
%ΔSize = (LDpost - LDpre) / LDpre   t/Z P
 Week 2 −0.07 (− 0.36, 0.07) −0.02 (− 0.12, 0.56) −3.238 0.001
 Week 12 −0.28 (− 0.91, 0.08) 0.13 (− 0.07, 0.85) − 6.120 < 0.001
%ΔCNR = (CNRpost - CNRpre) / CNRpre   t/Z P
 Week 2 −0.03 (− 0.57, 2.11) 0.09 (− 0.36, 4.56) −0.663 0.508
 Week 12 −0.04 (−1.10, 7.43) 0.28 (− 0.70, 2.88) − 1.962 0.050
  1. Comparison of the tumor ADC, LD and T2WI-CNR at three time points (mean ± sd) and the percentage change at two and twelve weeks after therapy (median and range) between the responder and non-responder groups