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Fig. 4 | BMC Cancer

Fig. 4

From: MASTL inhibition promotes mitotic catastrophe through PP2A activation to inhibit cancer growth and radioresistance in breast cancer cells

Fig. 4

MASTL depletion does not affect the viability of normal cells. HUVEC, HDFn, MCF7, and MCF10A cells were transfected with either control siRNA or MASTL.5 siRNA for 48 h. a, f The cells were analyzed by immunoblotting with the indicated antibodies. b, c, g Cell viability was determined by WST-8 assay. d, e, h, i The cell cycle was analyzed by FACS. The data represent typical results and are presented as the mean ± standard deviation of three independent experiments; **P < 0.01. N.S.: not significant

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