Fig. 1From: Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathwaysBenSer inhibits breast cancer cell growth by blocking leucine and glutamine uptake. Glutamine (a) and leucine (b) uptake over 15 min were measured in MCF-7, HCC1806 and MDA-MB-231 (MDA-231) cells in the presence or absence of 10 mM BenSer. c, data from (b) showing raw counts per minute (CPM). d-f, relative cell viability measured by MTT assay in MCF-7 (d), HCC1806 (e), and MDA-231 (f) cells cultured for 3 days in the presence or absence of 10 mM BenSer. Data represent mean ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; unpaired student’s t-test (a-b), 2-way ANOVA (d-f)Back to article page