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Fig. 9 | BMC Cancer

Fig. 9

From: Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character

Fig. 9

Immunolocalization of enzymes involved in the modification of CS chains. a-b Immunolocalization of chondroitin 4 sulfotransferase 2. a, Normal mucosa showing positive staining in crypts (arrow). b, Metastatic tumor showing a decrease in staining; magnification 40X. c-d, Immunolocalization of chondroitin 6 sulfotransferase 1. c, Normal mucosa, magnification 40X. d, Transition area between normal colon mucosa and tumor; the healthy tissue appears unmarked (asterisks), while the tumor shows intense immunoreactivity in the crypts (arrow), magnification 40X. e-f, Immunolocalization of uronyl-2-sulfotransferase. e, normal mucosa, (f), tumor, magnification 40X

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BMC Cancer

ISSN: 1471-2407

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