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Fig. 5 | BMC Cancer

Fig. 5

From: Nm23-H1 is involved in the repair of ionizing radiation-induced DNA double-strand breaks in the A549 lung cancer cell line

Fig. 5

Phosphorylation of checkpoint pathway related proteins detected by Western blot. Cells were collected at 0 h and 8 h after irradiation with 8 Gy X-rays. Checkpoint pathway related proteins were detected by Western blot. Note that radiation treatment increased the overall levels of pT68-Chk2, pS15-p53 and pS1981-ATM and the Nm23-H1 level also related to the amount of the phosphorylated protein. 1 A549; 2 A549-vector; 3 A549-nNm23-H1; 4 A549-shNm23-H1; 5 DOX+ A549-shNm23-H1. (**: p < 0.01)

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BMC Cancer

ISSN: 1471-2407

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