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Table 2 Association between RECQL Protein Expression and Clinicopathologic Characteristic (N = 322)

From: Low expression of RECQL is associated with poor prognosis in Chinese breast cancer patients

Characteristic

No.

RECQL protein expression

 

Low

High

p

No.

%

No.

%

Total

322

133

41.3

189

58.7

 

Age

      

  ≤ 50 yr

153

74

54.4

82

43.4

0.07

  > 50 yr

169

62

45.6

107

56.6

 

Tumor size

      

  ≤ 2 cm

112

48

45.7

64

43.5

0.73

  > 2 cm

140

57

54.3

83

56.5

 

 Unknown

70

28

 

42

  

Lymph node status

      

 Negative

168

75

59.1

93

51.1

0.17

 Positive

141

52

40.9

89

48.9

 

 Unknown

13

6

 

7

  

ER status

      

 Negative

100

44

43.6

56

35.9

0.22

 Positive

157

57

56.4

100

64.1

 

 Unknown

65

30

 

33

  

PR status

      

 Negative

101

33

33.3

68

43.3

0.11

Positive

155

66

66.7

89

56.7

 

 Unknown

66

34

 

32

  

HER2 status

      

 Negative

233

98

78.4

135

78.0

0.94

 Positive

65

27

21.6

38

22.0

 

 Unknown

24

8

 

16

  

TN

      

 Yes

29

7

7.8

22

14.8

0.19

 No

210

83

92.2

127

85.2

 

 Unknown

83

43

 

40

  

Adjuvant Therapy

      

 C

124

58

43.6

66

34.9

0.463

 E

20

7

5.3

13

6.9

 

 C + E

147

56

42.1

91

48.1

 

 No therapy

31

12

9.0

19

10.1

 
  1. Abbreviations: ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor-2; TN, triple negative; C, chemotherapy; E, endocrinotherapy; C + E, chemotherapy and endocrinotherapy