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Fig. 1 | BMC Cancer

Fig. 1

From: Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas

Fig. 1

Hyaluronan, CD44, HAS2 and HYAL2 stainings in brain tissue samples adjacent to tumor areas. Hyaluronan (a and b) staining intensity is higher in white matter (b) than in the cortex (a). Likewise, CD44 (c and d) staining intensity is stronger in white matter than in the cortical areas (c). However, there is noticeable CD44 staining in perivascular areas (d, d insert), where astrocytes show strong CD44 immunoreactivity. HAS2 staining is generally weak (e), but there are some strongly HAS2 positive neurons and glial cells (black arrows, e insert). HYAL2 staining is more prominent in the cortical areas whereas white matter is HYAL2 negative (f). Endothelial cells (white arrows) express strongly HYAL2 (f). Scale bar in F is 50 μm

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BMC Cancer

ISSN: 1471-2407

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