Oral cavity SCC | Â | Â | ||
---|---|---|---|---|
Variable | Univariate analysis | Multivariate analysis | ||
Hazard ratio (95% Cl) | P value | Hazard ratio (95% Cl) | P value | |
3A. Overall survival | ||||
Age (> 60 yr. vs ≤ 60 yr) | 2.25 (1.24–4.11) | 0.008* | 3.01 (1.38–6.56) | 0.006* |
Gender (male vs female) | 1.02 (0.55–1.88) | 0.949 | 0.89 (0.43–1.84) | 0.748 |
Smoking status a (ex & current vs never) | 0.56 (0.28–1.13) | 0.104 | 0.37 (0.17–0.82) | 0.014* |
Tumour grade b (3 vs 1&2) | 2.32 (1.24–4.32) | 0.008* | 2.29 (1–5.26) | 0.051 |
T stage (3&4 vs 1&2) | 1.68 (0.92–3.09) | 0.093 | 1.49 (0.7–3.16) | 0.301 |
N stage (2&3 vs 0&1) | 1.46 (0.78–2.73) | 0.243 | 1.97 (0.77–5.05) | 0.158 |
LC3B expression (high vs low) | 1.83 (1–3.37) | 0.051 | 1.67 (0.78–3.58) | 0.19 |
3B. Disease-free survival | ||||
Age (> 60 yr. vs ≤ 60 yr) | 1.69 (0.86–3.35) | 0.13 | 1.49 (0.63–3.49) | 0.361 |
Gender (male vs female) | 0.9 (0.45–1.8) | 0.767 | 0.77 (0.33–1.82) | 0.553 |
Smoking status a (ex & current vs never) | 0.93 (0.38–2.27) | 0.867 | 0.68 (0.26–1.82) | 0.446 |
Tumour grade b (3 vs 1&2) | 1.82 (0.87–3.83) | 0.114 | 2.16 (0.79–5.91) | 0.132 |
T stage (3&4 vs 1&2) | 1.09 (0.51–2.36) | 0.82 | 0.81 (0.33–2) | 0.643 |
N stage (2&3 vs 0&1) | 2.07 (1.02–4.22) | 0.045* | 3.42 (1.21–9.67) | 0.021* |
LC3B expression (high vs low) | 2.36 (1.19–4.67) | 0.014* | 1.82 (0.83–4) | 0.138 |