Table 2 Univariate and multivariate Cox proportional hazard analyses of clinicopathologic variables for overall and disease-free survival in oropharyngeal SCC patients

Age

(> 60 yr. vs ≤ 60 yr)

2.13 (0.96–4.72)

0.062

2.55 (0.86–7.58)

0.093

Gender

(male vs female)

0.64 (0.25–1.69)

0.372

0.23 (0.07–0.76)

0.016*

Smoking status ^a

(ex & current vs never)

1.49 (0.2–11.23)

0.697

0.64 (0.07–5.68)

0.691

Tumour grade ^b

(3 vs 1&2)

0.69 (0.27–1.81)

0.456

0.23 (0.07–0.78)

0.018*

T stage

(3&4 vs 1&2)

1.51 (0.69–3.31)

0.307

0.27 (0.07–1.03)

0.055

N stage

(2&3 vs 0&1)

1.39 (0.64–3.05)

0.407

5.21 (1.43–19.01)

0.012*

LC3B expression

(high vs low)

3.18 (1.31–7.71)

0.01*

4.02 (1.38–11.74)

0.011*

Age

(> 60 yr. vs ≤ 60 yr)

3.9 (1.35–11.26)

0.012*

3.24 (0.89–11.81)

0.075

Gender

(male vs female)

0.75 (0.24–2.39)

0.631

0.5 (0.11–2.35)

0.379

Smoking status ^a

(ex & current vs never)

NC

NC

NC

NC

Tumour grade ^b

(3 vs 1&2)

0.61 (0.19–1.98)

0.409

0.39 (0.09–1.78)

0.226

T stage

(3&4 vs 1&2)

1.46 (0.55–3.91)

0.447

0.53 (0.13–2.14)

0.372

N stage

(2&3 vs 0&1)

1.21 (0.45–3.26)

0.705

2.33 (0.57–9.49)

0.237

LC3B expression

(high vs low)

2.49 (0.87–7.09)

0.088

1.91 (0.57–6.36)

0.293