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Table 3 Univariate and multivariate analysis of prognostic factors for duodenal GISTs

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Prognostic factors Univariate analysis Multivariate analysis
β Hazard ratio (95% CI) P value β Hazard ratio (95% CI) P value
DFS
 Age 0.480 1.616 (0.874–2.987) 0.126    
 Gender −0.148 0.862 (0.470–1.582) 0.632    
 Anatomical location 0.108 1.114 (0.744–1.666) 0.601    
 Surgical procedure 1.517 4.559 (2.510–8.281) < 0.001    
 Tumor size 1.441 4.224 (2.769–6.442) < 0.001 1.406 4.082 (1.979–8.416) < 0.001
 Mitotic index 2.049 7.759 (3.751–16.048) < 0.001 1.294 3.648 (1.375–9.680) 0.009
 NIH risk category 1.457 4.294 (2.394–7.702) < 0.001    
 Adjuvant therapy 0.327 1.387 (0.514–3.742) 0.518    
DSS
 Age 0.338 1.403 (0.596–3.300) 0.438    
 Gender 0.324 1.383 (0.587–3.257) 0.459    
 Anatomical location 0.107 1.113 (0.649–1.909) 0.697    
 Surgical procedure 1.082 2.952 (1.274–6.837) 0.012    
 Tumor size 1.629 5.100 (2.640–9.853) < 0.001 1.339 3.816 (1.743–8.354) 0.001
 Mitotic index 1.719 5.580 (2.277–13.674) < 0.001    
 NIH risk category 1.035 2.815 (1.547–5.123) 0.001    
 Adjuvant therapy −1.388 0.249 (0.033–1.877) 0.178    
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health;
  2. DFS: disease-free survival; DSS: disease-specific survival; CI: confidence interval