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Table 3 Univariate and multivariate analysis of prognostic factors for duodenal GISTs

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Prognostic factors

Univariate analysis

Multivariate analysis

β

Hazard ratio (95% CI)

P value

β

Hazard ratio (95% CI)

P value

DFS

 Age

0.480

1.616 (0.874–2.987)

0.126

   

 Gender

−0.148

0.862 (0.470–1.582)

0.632

   

 Anatomical location

0.108

1.114 (0.744–1.666)

0.601

   

 Surgical procedure

1.517

4.559 (2.510–8.281)

< 0.001

   

 Tumor size

1.441

4.224 (2.769–6.442)

< 0.001

1.406

4.082 (1.979–8.416)

< 0.001

 Mitotic index

2.049

7.759 (3.751–16.048)

< 0.001

1.294

3.648 (1.375–9.680)

0.009

 NIH risk category

1.457

4.294 (2.394–7.702)

< 0.001

   

 Adjuvant therapy

0.327

1.387 (0.514–3.742)

0.518

   

DSS

 Age

0.338

1.403 (0.596–3.300)

0.438

   

 Gender

0.324

1.383 (0.587–3.257)

0.459

   

 Anatomical location

0.107

1.113 (0.649–1.909)

0.697

   

 Surgical procedure

1.082

2.952 (1.274–6.837)

0.012

   

 Tumor size

1.629

5.100 (2.640–9.853)

< 0.001

1.339

3.816 (1.743–8.354)

0.001

 Mitotic index

1.719

5.580 (2.277–13.674)

< 0.001

   

 NIH risk category

1.035

2.815 (1.547–5.123)

0.001

   

 Adjuvant therapy

−1.388

0.249 (0.033–1.877)

0.178

   
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health;
  2. DFS: disease-free survival; DSS: disease-specific survival; CI: confidence interval
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BMC Cancer

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