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Table 2 Comparison of clinicopathological factors of duodenal GISTs according to surgical procedure

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Characteristics Limited resection (n = 200) Pancreaticoduodenectomy (n = 77) P value
Age    0.782
  ≤ 60 101 (60.5%) 48 (62.3%)  
  > 60 66 (39.5%) 29 (37.7%)  
Gender    0.205
 Male 100 (51.3%) 32 (42.7%)  
 Female 95 (48.7%) 43 (57.3%)  
Anatomical location    < 0.001
 Superior portion 37 (19.7%) 3 (5.1%)  
 Descending portion 73 (38.8%) 52 (88.1%)  
 Horizontal portion 56 (29.8%) 4 (6.8%)  
 Ascending portion 22 (11.7%) 0  
Tumor size    < 0.001
  ≤ 2 cm 28 (15.1%) 3 (4.1%)  
 2–5 cm 102 (54.8%) 25 (33.8%)  
 5–10 cm 37 (19.9%) 32 (43.2%)  
  > 10 cm 19 (10.2%) 14 (18.9%)  
Mitotic index    < 0.001
  ≤ 5 144 (83.2%) 32 (52.5%)  
  > 5 29 (16.8%) 29 (47.5%)  
Morphology    0.146
 Spindle 100 (94.3%) 39 (86.7%)  
 Epithelioid 0 1 (2.2%)  
 Mixed 6 (5.7%) 5 (11.1%)  
NIH risk category    < 0.001
 Very low 23 (12.8%) 2 (2.8%)  
 Low 87 (48.6%) 15 (21.1%)  
 Intermediate 2 (1.1%) 0  
 High 67 (37.4%) 54 (76.1%)  
Neoadjuvant therapy    0.472
 No 194 (97.0%) 73 (94.8%)  
 Yes 6 (3.0%) 4 (5.2%)  
Adjuvant therapy    0.362
 No 165 (82.5%) 67 (87.0%)  
 Yes 35 (17.5%) 10 (13.0%)  
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health