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Table 2 Age, gender and general biochemical parameters in control subjects and HCC patients

From: Increased systemic zonula occludens 1 associated with inflammation and independent biomarker in patients with hepatocellular carcinoma

Parameters Controls (n = 30) HCC patients (n = 30) Mann-Whitney Test
p value
Age (years)
 Mean ± SD 53.47 ± 6.64 54.37 ± 11.33  
 Median (IQR) 55.0 (48.75-58.00) 56.50 (50.75-62.00) 0.213
Gender (Male/Female) 20/10 20/10  
Total bilirubin (mg/dl)
 Mean ± SD 0.71 ± 0.09 2.50 ± 0.4.65  
 Median (IQR) 0.70 (0.68-0.73) 1.20 (0.78-1.73) < 0.0001
Direct bilirubin (mg/dl)
 Mean ± SD 0.23 ± 0.05 0.77 ± 1.19  
 Median (IQR) 0.20 (0.20-0.30) 0.40 (0.20-0.80) < 0.0001
Total protein (gm/dl)
 Mean ± SD 7.33 ± 0.36 6.79 ± 0.94 < 0.01
 Median (IQR) 7.30 (7.20-7.60) 6.85 (6.18-7.55)  
Albumin (gm/dl)
 Mean ± SD 3.97 ± 0.32 3.14 ± 0.67  
 Median (IQR) 4.10 (3.60-4.30) 3.05 (2.68-3.60) < 0.0001
AST (IU/L)
 Mean ± SD 22.90 ± 6.61 118.2 ± 99.87  
 Median (IQR) 21.00 (19.75-28.00) 78.00 (51.00-148.5) < 0.0001
ALT (IU/L)
 Mean ± SD 24.90 ± 8.40 60.79 ± 38.13  
 Median (IQR) 23.00 (19.00-32.25) 45.00 (35.00-79.50) < 0.0001
γGT (IU/L)
 Mean ± SD 27.47 ± 10.46 142.5 ± 136.0  
 Median (IQR) 27.00 (19.50-32.00) 92.50 (57.00-159.0) < 0.0001
ALP (IU/L)
 Mean ± SD 176.2 ± 30.55 663.0 ± 654.2  
 Median (IQR) 180.0 (155.8-196.3) 480.5 (282.8-680.0) < 0.0001
  1. ALT alanine transaminase, AST aspartate transaminase, γGT gamma glutamyl transpeptidase, ALP alkaline phosphatase